ID   A0A2G5PGK7_9MYCO        Unreviewed;        96 AA.
AC   A0A2G5PGK7;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Cation:proton antiporter {ECO:0000313|EMBL:PIB77447.1};
GN   ORFNames=CQY22_000265 {ECO:0000313|EMBL:PIB77447.1};
OS   Mycolicibacterium brumae.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=85968 {ECO:0000313|EMBL:PIB77447.1, ECO:0000313|Proteomes:UP000230551};
RN   [1] {ECO:0000313|EMBL:PIB77447.1, ECO:0000313|Proteomes:UP000230551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP1034565 {ECO:0000313|EMBL:PIB77447.1,
RC   ECO:0000313|Proteomes:UP000230551};
RX   PubMed=29030295; DOI=10.1016/j.meegid.2017.10.013;
RA   Tortoli E., Fedrizzi T., Meehan C.J., Trovato A., Grottola A.,
RA   Giacobazzi E., Serpini G.F., Tagliazucchi S., Fabio A., Bettua C.,
RA   Bertorelli R., Frascaro F., De Sanctis V., Pecorari M., Jousson O.,
RA   Segata N., Cirillo D.M.;
RT   "The new phylogeny of the genus Mycobacterium: The old and the news.";
RL   Infect. Genet. Evol. 56:19-25(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC       family. {ECO:0000256|ARBA:ARBA00009212}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIB77447.1}.
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DR   EMBL; PDCN02000001; PIB77447.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5PGK7; -.
DR   STRING; 85968.GCA_900073015_01792; -.
DR   OrthoDB; 3733837at2; -.
DR   Proteomes; UP000230551; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR007208; MrpF/PhaF-like.
DR   PANTHER; PTHR34702:SF1; ANTIPORTER SUBUNIT MNHF2-RELATED; 1.
DR   PANTHER; PTHR34702; NA(+)/H(+) ANTIPORTER SUBUNIT F1; 1.
DR   Pfam; PF04066; MrpF_PhaF; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230551};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   96 AA;  10119 MW;  D3A7DCED61F0DE13 CRC64;
     MSTVFAIAAV MMTLAAVLTM YRLLAGPSTL DRLVALDTLI AVTMGSIGVW AAYSHDTTVT
     YSLAALALIS FVGSVSIARF RVPDTVDPLD RDGGRP
//