ID A0A2G5SLE4_9PELO Unreviewed; 789 AA.
AC A0A2G5SLE4;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 08-NOV-2023, entry version 18.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN Name=Cni-gap-2 {ECO:0000313|EMBL:PIC15752.1};
GN Synonyms=Cnig_chr_X.g22608 {ECO:0000313|EMBL:PIC15752.1};
GN ORFNames=B9Z55_022608 {ECO:0000313|EMBL:PIC15752.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC15752.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC15752.1}.
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DR EMBL; PDUG01000006; PIC15752.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5SLE4; -.
DR Proteomes; UP000230233; Chromosome x.
DR CDD; cd05136; RasGAP_DAB2IP; 1.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF125; RAS GTPASE-ACTIVATING PROTEIN RASKOL; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00616; RasGAP; 2.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230233}.
FT DOMAIN 147..341
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 447..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..789
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 789 AA; 88898 MW; B4664668EA9C4AA0 CRC64;
MRGEYDPWDP SSHNSAIIPY SLASVYPSIE NLQAEEFSNE NGRVKNMLKT FLWSFKLKKN
YVRVSTLFGE YCRYTVNNTQ QDSSASRIAS ALGGKSSSQE VQSIRIKARW QSVDVLPLRV
YDRLSELLTY NYLDLCQQLE PVLNVRDKED FATSFVRVMY KQNCAVEYLA DLVMAEIGKL
DNDNLMFRGN TVATKSMESF MKLVASDYLE FTLRDFIMTV VACEDSCEVD PQRLGNVPSS
VLDKNRALLT RYVEVAWTKI INSVHMVPKI LGKVFATLRL RLEAQNRGEH AETIISSSIF
LRFLCPAILS PSLFNLVAEF PSINNARNLT LIAKTLQNLA NFSKFGGKEP HMEFMNTFVD
REWNRMHEFL LEISTESKSV GPDKSADAIV DAGKELSLIG SYLEEVWSPL LQEKNLNKPL
GEVKQVLTEL AEAKRRPDHA IFHSPMVQQP SSDYENSPQQ NVVPRHENVP AYRSTPPTGQ
ATVMGRSMNR PATHLMTSDD YVLSSAFQTP SLRPARLSDE TGTSSSRTSD KTTSSAEIRD
DTDSDFELRD ELGRGMRNRK RLPRTDASPS SSQQASSGYM SNNPSRSSYS NSSSSSPVER
MAALSIANPV FGPGPSAGFS IPAEPKEIVY QKRASPPPYD PEVHQYHYQP MQVYAVPPDC
QLSPRGQSVP GIASQNRLSL PRTNPRASRT STLLRPSVVN VPDDWERQGD YWRDTHQMDQ
YRARDEMIKN QAREIERLTR ENLELKNQIM SSTKLVDSKR SDSGASEDSY DSLSSLDRPT
RKSLVVLPN
//
