ID   A0A2G5STB1_9PELO        Unreviewed;       407 AA.
AC   A0A2G5STB1;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN   Name=Cni-hsd-3 {ECO:0000313|EMBL:PIC18267.1};
GN   Synonyms=Cnig_chr_X.g24220 {ECO:0000313|EMBL:PIC18267.1};
GN   ORFNames=B9Z55_024220 {ECO:0000313|EMBL:PIC18267.1};
OS   Caenorhabditis nigoni.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC18267.1, ECO:0000313|Proteomes:UP000230233};
RN   [1] {ECO:0000313|Proteomes:UP000230233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA   Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA   Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT   "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT   competition proteins.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIC18267.1}.
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DR   EMBL; PDUG01000006; PIC18267.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5STB1; -.
DR   STRING; 1611254.A0A2G5STB1; -.
DR   Proteomes; UP000230233; Chromosome x.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230233}.
FT   DOMAIN          32..298
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   407 AA;  46660 MW;  75925B99D8892EA9 CRC64;
     MLENYRECVL NIRPNVINIS GDSIMNQRDH YVITGGAGFL GSQLIAALQK NGDMTQCVVI
     DPSPPRHYDN IQFDRAFVTY VQEKFQEDHV LDSVLPNAST VFHLCSIGHT GKYGARRYQD
     EVYKINVKGT EKLISKCRKY KVPRFIYSSS IAVVFVGKPL FDVTEEMPYP EDHEFLDIYS
     KTKAEAEKCI ISQSCPEFKT TCLRFRAIYG PQDSVVAEKV VNMVGMNFFR MKICRESEET
     SSNMSSGRNC GLALHLANQA LMDERKPHGK AYFIHDGEEI QQYAVWTPLI KALGKQPPTF
     RCPYFLVSPF IALISFFCHE ILKISPPMTR FELEVLVTTN TYSIEAAKRD LDYRPTGNHF
     QEAVDYYRVD SKDKIEAHQP TAYLDYDDLI FILILLLWTV SLLWSSH
//