ID A0A2G5SVC1_9PELO Unreviewed; 822 AA.
AC A0A2G5SVC1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Ion transport domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Cni-kqt-1 {ECO:0000313|EMBL:PIC18811.1};
GN Synonyms=Cnig_chr_X.g24571 {ECO:0000313|EMBL:PIC18811.1};
GN ORFNames=B9Z55_024571 {ECO:0000313|EMBL:PIC18811.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC18811.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC18811.1}.
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DR EMBL; PDUG01000006; PIC18811.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5SVC1; -.
DR STRING; 1611254.A0A2G5SVC1; -.
DR Proteomes; UP000230233; Chromosome x.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 6.10.140.1910; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47735:SF9; POTASSIUM VOLTAGE-GATED CHANNEL KQT-LIKE SUBFAMILY, INVERTEBRATE; 1.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01459; KCNQCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..378
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 624..739
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 55..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..786
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 822 AA; 91914 MW; AFDD36B6BFE82D34 CRC64;
MSQASGEDND YADPMSPESP MTPDGMILAR MPWHPGLEGN WNTVKSVSTA MLNGDETDRA
APSDEQQEAG SSSQIGQESR KTVVFQEPDT GFPNEHDQLT ALHDSEEGNR KMSLVGKPLT
YKNYRTDQRF RRMQNKMHNF LERPRGWKAA SYHLAVLFMV LMCLALSVFS TMPDFEVKAT
IVLYYLEIVF VIWLATEYIC RVWSAGCRSR YRGISGRIRF ATSAYCVIDI IVILASITVL
CIGATGQVFA ASAIRGLRFF QILRMLRIDR RAGTWKLLGS VVWAHRQELL TTVYIGFLGL
IFSSFLVYLC EKNTNDKYQT FADALWWGVI TLSTVGYGDK TPETWPGKII AAFCALLGIS
FFALPAGILG SGFALKVQQH QRQKHLIRRR IPAAKLIQCL WRHYSAAPES TSLATWKVHL
ARELPPIVKF TPNNGSNNAT GLINRLRQST KRSPNSQMQG PTSNFPPSSK NLSVPRVHDT
ISLVSTSDIS EIEQLGALGF SLGWKSKSKY SGSRKAADDS VLQSRMMAPS NTNLDDMRRR
SRRSASLCRV VNNNGQHLRP SQPRATLSDG DVIGDYSLMM APIYQWCEQM VQRNSGPGED
GVWSQLSQLT TCATRRAEDI SDGDEEENIG YQPQTMEELT PALKNCVRAI RRIQLLVARR
KFKEALKPYD VKDVIEQYSA GHVDLQSRVK TVQAKLDIIC GKNIEKLEPK ISMYSRIATL
ENTVGKMDKK LDMMVELLMS RQPGSRVFSQ STSPRGEIVS EPNTGRIDLT RSRRSVASTD
NEMYTARSHS PGGPAIRMAE EEDDEAFDES SPLNNGPSTS SC
//
