ID A0A2G5SWV6_9PELO Unreviewed; 802 AA.
AC A0A2G5SWV6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Nuclear receptor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Cni-nhr-25 {ECO:0000313|EMBL:PIC19413.1};
GN Synonyms=Cnig_chr_X.g24975 {ECO:0000313|EMBL:PIC19413.1};
GN ORFNames=B9Z55_024975 {ECO:0000313|EMBL:PIC19413.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC19413.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC19413.1}.
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DR EMBL; PDUG01000006; PIC19413.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5SWV6; -.
DR Proteomes; UP000230233; Chromosome x.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd07167; NR_DBD_Lrh-1_like; 1.
DR CDD; cd06930; NR_LBD_F2; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR016355; NR5-like.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24086:SF15; NUCLEAR HORMONE RECEPTOR FTZ-F1; 1.
DR PANTHER; PTHR24086; NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 274..349
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 540..802
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 90334 MW; D210085A1F65D168 CRC64;
MEEEQKPFLF DKPEGNFSFD ANSSAASSPK HLNLESSPFG KTNIEVKKED SYLFYPPKDN
SSEDADLSPA SSYELLNLKS SPFFETNSEV KEEKSFKSSE DANLITDADP GYACFDLSSY
LQGNAEVKEK PPSLLDLLRV YLSLPLLKSE VKEEIISLEG FPRDNSSDNA YAEMESQRYC
KGKKKKKSDA SSAKTPYSST ITNSITDTPT EDKNVGSKAT SEGPGVDLQL QPASIQSPHI
GSRWRIHWSN TDGGVLRRQM TDVERMVLRP NHEGEQCPVC GDRVSGYHYG LLTCESCKGF
FKRTVQNKKQ YQCSADANCH VDRTCRKRCP SCRFQKCLTM GMKMEAVRAD RMRGGRNKFG
SFYKRDRAHR LQRNAMRVTV IPSSGITSQP QTFYTPADHQ VSSSTTDQNT HIHYYDQTKV
KTEFIKTEYD AHLQSPTLSS STNQQTLLNT TNEDHLLRFP TTYPLAEVKQ EPFDYSEHHF
VHHPLLEYQG YTSTANYAPM MPIPTVTTAQ SVVTSTSSTT TGRVAEQTRT SPVLPLCPAP
TEKTVDHFYN SNMAEMCKTL PDDSQIIRIF NAAKGIKGEA HSFAVTVADE NLKVIVDWAK
NNQLFGKLQL DDQMNLLQTS WSTVHLVDIT NAMIHGNLSP TYKITTGEDV SVGAVALLGY
RLYVNTWNDI VNRLRNMGFT KFDYCAFRFL ALFDQSMDHF QAVSTARSRV LQAWAEVRCS
FVSGFMSIFE EIRRLSHDAV RYLWSLQSNF PELWASLRPD TSLVLEMIKT SATRPTDVTS
TVPHISVPLQ QTTYAPVVYM TS
//
