ID A0A2G5TLD5_9PELO Unreviewed; 417 AA.
AC A0A2G5TLD5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 13-SEP-2023, entry version 14.
DE RecName: Full=BPTI/Kunitz inhibitor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Cnig_chr_V.g20127 {ECO:0000313|EMBL:PIC28100.1};
GN ORFNames=B9Z55_020127 {ECO:0000313|EMBL:PIC28100.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC28100.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC28100.1}.
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DR EMBL; PDUG01000005; PIC28100.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5TLD5; -.
DR STRING; 1611254.A0A2G5TLD5; -.
DR Proteomes; UP000230233; Chromosome v.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00191; TY; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR Gene3D; 4.10.800.10; Thyroglobulin type-1; 2.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR000716; Thyroglobulin_1.
DR InterPro; IPR036857; Thyroglobulin_1_sf.
DR PANTHER; PTHR47248; PROTEIN CBG06772; 1.
DR PANTHER; PTHR47248:SF7; PROTEIN CBG19214; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF00086; Thyroglobulin_1; 2.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SMART; SM00211; TY; 2.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF57610; Thyroglobulin type-1 domain; 2.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS00484; THYROGLOBULIN_1_1; 1.
DR PROSITE; PS51162; THYROGLOBULIN_1_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00500}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 79..128
FT /note="Thyroglobulin type-1"
FT /evidence="ECO:0000259|PROSITE:PS51162"
FT DOMAIN 132..202
FT /note="Thyroglobulin type-1"
FT /evidence="ECO:0000259|PROSITE:PS51162"
FT DOMAIN 236..289
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DISULFID 169..176
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00500"
SQ SEQUENCE 417 AA; 46459 MW; 11A1C911049A6E3E CRC64;
MNTSSKLCRT HYPKVRYKKE TIMTRKAYYP VIICLFFVFF FLPSPTESTV KCFKGFSGDG
RPFKQRLCQT EYCIKNPATG PCTLNNDGLK CNENGYYATV QCNKESCYCV TPHTASIAYD
TRTNSPKTAP KCGTCLVYLQ KLFANGDPPE NSFVPKCDVG DGDFEPVQCD STKNQCYCVD
TVTGREIPGT KKALSNTTKM NCMKIDFSID SVAFPTFEKA DALKPKSELI IGRPSCAHNR
NAGYICSQNK TSIRYWFDVE TFQCLAFEHK GCGGNQNSYR TSQECYSDCV LADYFSCALQ
SEPAKMSNGQ AYICPESGPQ PPPGRTTTTT PGPQLKDGCP RGYTCQMGPF FGFCCEESLT
NRYQTAFSTK CKNNKPSLQV QHDGYSSGML GKSCSDNFCP KTHNCEHNEF FAFCCPK
//
