ID A0A2G5TV98_9PELO Unreviewed; 947 AA.
AC A0A2G5TV98;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Cni-snx-13 {ECO:0000313|EMBL:PIC31212.1};
GN Synonyms=Cnig_chr_IV.g11982 {ECO:0000313|EMBL:PIC31212.1};
GN ORFNames=B9Z55_011982 {ECO:0000313|EMBL:PIC31212.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC31212.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC31212.1}.
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DR EMBL; PDUG01000004; PIC31212.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5TV98; -.
DR Proteomes; UP000230233; Chromosome iv.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd08719; RGS_SNX13; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037896; SNX13_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..290
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 379..498
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 572..693
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 527..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 947 AA; 108301 MW; 0E832BE4762CA37B CRC64;
MSNRFYILLG GLLFLSTFGL TGVIVVPLSV ICFLAGFLYI VYQTGLEKSA ELDEKLAFRL
QKYKFPSGIE QLLKNGKRLT EQNQYEEVHS MSNSPQLDLV LEEILGYITR DYIGFWYKNL
SNDKLFEQSL KRTSRRSIAS LTQCLRQVEW VPLITRDVVD DFASHLRLFR KAKERTTFQM
KDNGNSDKSR TVEDLDAELL SNFFDFELEM EKTLCRDLLS TTPHYENAYL HDLVDIILYL
VMPPEDFRCR PLRFLLREVV VRKVILPTLD YLSNPNEIFQ LIVWLLSEVE PKPDDFLACL
SSSTCIEELE SVLKEIVNEK TVMRGKDSGG EQDTFVKQQL ASLNFVESLV QRRIDYLGSQ
DSAFLSKFGE DGDQLVQLPL HVILTNSTAL SQFCEFLKSA GGQNYIDFYL AIEGFKVSVE
HQMRSLAKGE LSESDAYETV KEAAKYMYDQ YLSEEAITRV PLDDALMTKF LQRLKNDEPH
DLWFEAIQEK VFDVLKTDDH FFPAFKKSPA YVKMLLDLEI IDEDRNDPTM SECDSVTSFS
SQEKSEDESR CDSALRKLPL EIDGSAPLEG EPVMTAIVET LGIGHQGKQT YALYNVRVTR
CVDGLEVSSW NVIRRYSDFH SLHQNLVQKF PKLATLSFPG KKTFNNLDSQ FLEKRTKALN
LYLTCVLQPS LLRNYPDMDR HVFDFLSQKK YANSDPLTKK LMSAMFDPIR NGVKAVGNTV
MAVPDQVFEG VTKMGAGINN AAKIIINPIS STTTPNRPPE METDRVAASL TDTEAENIPL
RVLVLVVSEV FGAQGSAWFR RQLVTVIRHI VTPFGTSINK RIVDIVNWLT SEQQVGGYLT
SFKKSMWPDG ELATEYVEKP AEFHHRTRLL AKTLMLSSLP DELRMILGTN VSYKGINTIS
EAFQNKNLNR RLLYVLLERF LIKVFPSNRF EKIFAQLHSK SPRTKKM
//
