ID   A0A2G5U423_9PELO        Unreviewed;      1414 AA.
AC   A0A2G5U423;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=TRPM SLOG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   Name=Cni-gtl-2 {ECO:0000313|EMBL:PIC34279.1};
GN   Synonyms=Cnig_chr_IV.g13983 {ECO:0000313|EMBL:PIC34279.1};
GN   ORFNames=B9Z55_013983 {ECO:0000313|EMBL:PIC34279.1};
OS   Caenorhabditis nigoni.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC34279.1, ECO:0000313|Proteomes:UP000230233};
RN   [1] {ECO:0000313|Proteomes:UP000230233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA   Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA   Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT   "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT   competition proteins.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIC34279.1}.
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DR   EMBL; PDUG01000004; PIC34279.1; -; Genomic_DNA.
DR   Proteomes; UP000230233; Chromosome iv.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   PANTHER; PTHR13800:SF45; GON-TWO LIKE (TRP SUBFAMILY); 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        906..926
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        975..994
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1038..1058
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1114..1135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          176..439
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          909..1145
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1367..1414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1367..1383
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1384..1398
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1414 AA;  162619 MW;  E6D320A5DFB356AC CRC64;
     MINETTMKTN GINGETIGEN DGEEEEEEGN EDRNRSSSFL RLLNAPRNSV CNANTVHSIS
     SFRSDHLSRK STHKLLDNPN LFAIELTEKL SPPWIENTFE KRECVRFTAQ SKDAERCGCG
     RPLAAHSSAS RIFYTLPYHI IDKEQEVWTI ANNTQTSTTD AFGTIVFQGG AHAHKAQYVR
     LSYDSEPLDV MYLMEKVWGL EAPRLVITVH GGMSNFELQE RLGRLFRKGM LKAAQTTGAW
     IITSGLDSGV VRHVAKALDE AGISARMRSQ IVTIGIAPWG VIKRKERLIR KNEHVYYDVH
     SLSVNANVGI LNDRHSYFLL ADNGTVGRFG ADLHLRQNLE NHIATYGCNG RKVPVVCTLL
     EGGISSINAI HDYVTMKPDI PAIVCDGSGR AADLISFAAR YINTDGTFAV EVGEKLKNLI
     KMVFPESDQE GLLNRITECV IRDDLLRIFR YGEEEEEDVD FVILSTVLQK QNLPPDEQLA
     LTLSWNRVDL AKSCLFSNGR KWPSDVLEKA MNDALYWDRV DFVECLLENG VSMKNFLTIN
     RLENLYNMDD VNSAHSVRNW MENFDSMDPH TYLTIPMIGQ VVEKLMGNAF QLYYTSRSFK
     AKYDRYKRLN QSSYFYRKRK IVQKELFKKK SDDQIDETSE EDFSFSYPFN DLLIWAVLTS
     RHEMAKCMWI HGEDAMAKCL VAIRLYKATA KIAEDEYLDV EEAKRLFDNA VKCREDAIEL
     VDQCYRADHD RTLRLLRMEL PHWGNNNCLS LAVLANTKTF LAHPCCQILL AELWHGSLKV
     RSGSNVRVLT ALICPPAILF MAYKPKHAKT ARLLSEETQE DIPYPRESIT STTSNRYRYS
     KGPEDQKETL LEKGNYAKKV TIISSRKNSG VASVYGSASS MMFKRDPQLS KFEKFRAFYS
     APITKFWSWC IAFLIFLITQ TCILLLETSL KPSKYEWILL IYTVTLSVEH MRKLLTSEGS
     RINEKIKVFY AKWYNIWTSA ALIFFLVGYG FRLVPMFRHS WGRVLLSISN VLFYMKTFEY
     LSVHPLLGPY IQMAAKMVWS MCYIVVLLLV PLMAFGVNRQ ALTEPKIKDW NWLLVRNIFY
     KPYFMLYGEV YAGEIDTCGD EGTRCFPGYF IPPLLMVVFL LVANILLLNL LIAIFNNIYN
     DSIEKSKEIW LFQRYQQLME YHDSPFLPPP FSIFAHVYHF IDYIWNLRSK RPDTKRFRSE
     HSIKWSVTED EMKRMQDFEE DCIDTLTRTR RLKLDTKEPL NMTDLTELTC ERVHDLMQEN
     FLLKSRVYDI ETKIDHIANS SDEVVQILKN KKISQNFAAS CLSLPETSIE VPKLTKPLID
     YHLSPVVIEE RLATRSPLLA NLHRDHTLRK YDDANFQAGN LQRRTRLHSS SCSISQDMKE
     MRTSASSRNL KRQDSEELTV SSHGGYDSDI SGPD
//