ID A0A2G5UAX2_9PELO Unreviewed; 1460 AA.
AC A0A2G5UAX2;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
GN Name=Cni-cdh-5 {ECO:0000313|EMBL:PIC36491.1};
GN Synonyms=Cnig_chr_IV.g15461 {ECO:0000313|EMBL:PIC36491.1};
GN ORFNames=B9Z55_015461 {ECO:0000313|EMBL:PIC36491.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC36491.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC36491.1}.
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DR EMBL; PDUG01000004; PIC36491.1; -; Genomic_DNA.
DR Proteomes; UP000230233; Chromosome iv.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 8.
DR Gene3D; 2.60.40.60; Cadherins; 8.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24026; FAT ATYPICAL CADHERIN-RELATED; 1.
DR PANTHER; PTHR24026:SF125; FAT-LIKE CADHERIN-RELATED TUMOR SUPPRESSOR HOMOLOG; 1.
DR Pfam; PF00028; Cadherin; 4.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 8.
DR SUPFAM; SSF49313; Cadherin-like; 8.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 8.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1460
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013647009"
FT TRANSMEM 1294..1318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..164
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 182..271
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 299..398
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 414..510
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 728..833
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 834..945
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 956..1059
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1082..1184
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 516..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1388..1407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..701
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..721
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1460 AA; 159635 MW; FE0C5F8A7F620681 CRC64;
MMRHRRRSIF LSLILLFSSA STVICQEPQI SDQPIVSNHA PVLQVSSTEG FLAETAEIGT
TVRVSPNSQS ESLQILVNDE DLQPGMPPAT YQYILTGLGA TIFAVDQRGY VYLNVPKIDA
DPPNPSTYQL NVEAREVNTI PTRRSDPVTI TIHILDVNDN SPQFEQPIYM ANTTASGEER
DVVRVVATDV DSGAFGQVSY AIAQVTNGAE DKFRYEPATN MLLATGNLVA GERYQVVIEA
TDGGGRSSQA IVIVLAMDPT QLTFSSLAPL PGMETFMPNP MAMATTPGTM VTSAESEETI
QTFVTEVNEN TPANTVVVSL GDESSKDLTY FNIVGGNEEG KFAIDDAGTI VTADELDREK
TAMYSLQVET RSRNPDQHLY WTLVQVTVMD VNDNAPIFTD PQPIRLRLSI DDIEQLTANM
IIGKIGVEDA DADDNGRLEL RIMPPHNKLF AISNEGILSV NGDFTAAHFG EHDLTIVARD
HGEPSLETRA RVQISIFGTL ITMATVAPTN EVFEYTSSVE EEPQTTNPDE FLQTVTMPPS
TKNQVPQQIF SSFPAPSEQT NAPEPEFPQF PTFPTLSPHP QIDEETEEEE ETEYPDTVPT
TGTVPPTSDY SEEYGQEASS STVPPSTEQV QGIWSETPEF PESASSENPI TALPEFPENV
LEISSTFAPD TPPKIAPETS ENPDSTWQEE TETSQELPSH PTTKMAPPPV TQAPPPLPAQ
KRLAPVFKPS QITVQIDENE SQVEITKAHA TYPDGLPGTI TYVLHKGDSS LFSVSSYSGS
VNLLRALDAE MNSTVTIQVS TSEAQTLEVD PKLAHFVSIT INVADKNDWI PNFESASYEF
DVKEDTLPGT IVGQVNAFDQ DRDDPNNRIR YRLLSAGGLE AHFNVNAESG LITLARPIDA
FAGEKITLRI EGADSGMPPL SSTTTVLINV VTTSSHLIPD ASPVSNTPNE GELQFSLRNY
TASVSEAVRP PHLVQVLSVM NKPADTRFII CNIVSGNYRG AFGVTAGNDG NCELRTQMEL
DRETVERYLL NVTVTAGSQT DYALVSITVL DVNDNVPRFV YDSDLGLTTY FGAVSSVANA
FTRVLTVKAE DADLGNSSLV NYALDPLSAH SKYFSISPFG EISTKQSMST ILSRNRLQFF
EFRVSACDSP ISGQQLCSKA DVVVNVIGST NRFKMIIYGL NPQQLKKHEK DLVKSIRQFT
GSCNLLTIEK MIEHTAIENQ IRTDIYWYAV NPTTKKICKK QDIRKLFETS NVQLIAGKVQ
PWFRLERISE DAGEEGGMSG AGGILSTNWK TSNILLLILA VAIALGAIIA LCAVCVFWSR
YKTAQRNASN FSHSYPQKLG PIYHPSMAGI DPRTEFDYET QNVNMLISDE DLTMKSGSVG
VPAHQRMGFG GPGGPPGPGN GNQSYRTYGY RPAQSTAYEG DFSIEESMYA INPSGRLDPV
TNRVILPTNL PRTTNVYRQS
//
