ID A0A2G5UCN5_9PELO Unreviewed; 697 AA.
AC A0A2G5UCN5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN Name=Cnig_chr_IV.g15981 {ECO:0000313|EMBL:PIC37307.1};
GN ORFNames=B9Z55_015981 {ECO:0000313|EMBL:PIC37307.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC37307.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC37307.1}.
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DR EMBL; PDUG01000004; PIC37307.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5UCN5; -.
DR Proteomes; UP000230233; Chromosome iv.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638:SF10; CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 210..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 574..693
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 697 AA; 81757 MW; 90D6A2E4F4B2D2F2 CRC64;
MKNLGKSRNR SESNYYENES PKWIPQATER PTYYTHHDTD DDDDLPYDYG EGPPTSSSHP
LAGATSSFHQ KPSRWAMVRE KSPQIISKEA KLQDKRRQLD SNKGRVRLKF EKSAKQRNEE
IAQNNSFSDV VKTAMMLRTW ISAMEHDERE SEPERDRTTT NAEPTTENGD ILPAPPVFVP
RLSGWTQTKE YLKDKWLQLR YFYVTENSTF FYYWSALITI GIIYNMCAMV IFIFDDIHQG
YFKQWLYINM FFDVCYILDC LIGSRLAFNY EGNEVRDTSK MLKNYKKSAR AVYDVLCLFP
LDFALFIWSQ ASIIRIFRMI KIYRLYEFII LTQRRTDWPH FMKILFLTTA CGILFHWNAC
VYFLFSLFEG LTEDDTNAFG FSYYKVFDPR FPSCDALYDE SCWYPEDDDV LDIRDERPKY
MHQMYQFWKD KYDIFSMGNF SREYSMTLYW SSLTITKCGQ QPWPSRSPQN ALEIFDTLIG
VLVFATIIGG VGSVVTQMSQ NVNTFREMMD GIKFYMNYRG VQWQIQERVL NCFLYLNSHN
QLYEEDEILS SLPPRIQAKI ASDLHAETLS HVLLFSKCEK RMIDELVLLV KQQVFSPNDY
LCRKGELAQE MFIVKKGKLA IIDDETGIEL DVLEEGCTFG ELSVIHVPGN QLGDRRSVSL
RAIGYSDVFV LHKDDVSKLL NEYPEERVRL LENGEHI
//
