ID A0A2G5UK91_9PELO Unreviewed; 985 AA.
AC A0A2G5UK91;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN Name=Cnig_chr_III.g11488 {ECO:0000313|EMBL:PIC39985.1};
GN ORFNames=B9Z55_011488 {ECO:0000313|EMBL:PIC39985.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC39985.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC ECO:0000256|RuleBase:RU004020}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC39985.1}.
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DR EMBL; PDUG01000003; PIC39985.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5UK91; -.
DR Proteomes; UP000230233; Chromosome iii.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 3.
DR Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015:SF206; HEAT SHOCK FACTOR PROTEIN; 1.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00046; Homeodomain; 3.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00389; HOX; 3.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 3.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 962..984
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..110
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 738..789
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 874..934
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 61..111
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 740..790
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 876..935
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 166..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..623
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 985 AA; 109977 MW; 3C8CB3FFCFD56FEF CRC64;
MSKFESSQIG KLQKTVLTET SSGSSSSSNS ARNSAPDSNS VSMDLFSFDS ISSIFARYLS
PLQSEALEQQ FAINKHLTPE IQAELARRTN LTESEVKIWF QDRRIRQERE ENECNGKDTD
SFVKNYVNLP DASKPLFSFE AKKLPENFGF SPFPWDYSYW QENRDYAAKN QPPPDHVEFI
GVNGNSKGSA EGDGLSLFGS PSMRSGHISD SPNEGFHGER NDNHGPQQSD GDILQNKLLR
AAKMWKARKL LQEESRLSTQ GAAPSPLNNG STLPQSGSST PAPSTTGSLL QPLFVSSRPT
TAAGFGGGSS SAAPAPMLKE EDPKNETSNQ APESVKDVQP SEKPSVGKCK ETATDSNSGD
TSDGFAFDDK NQQGAAGRLI PNEDKLPVFL IKLWTIVEDT NLQSIVHWDE SGASFHIADP
DSFCRNILPH FFKHNNLNSL IRQLNEFGFR KMTPESDQDH LEFSHPYFVQ GRPELLSKIK
RKKPSKETEG KVVNEQTQQS LDMVMAEMRS MREMAKNMED KMNKLTKENR DMWNEMESMR
RQHEQQQPSD MAPSDGTFEK KMLESANDRQ QNKLLLAAKM WKTQKQLEEE SRLSTQGAAP
SPLNNGSTLP QSGSNTPVPA TTGDLLKPLF VSSTPTTAAG FDGGSSTVAS APMLKEEDPI
DETSNQASES VKDVQPSKKP SAVKCKEMAT DSNSGDTSGV NGFAFHDSMS SLLARLTTGN
GNQNSGIRKL RDVGLGNLSP LQSHDLEQQF SINKELTPEI QAELARRTNL TESEVKIWFQ
DRQYRQRRER NNEAAKKARF LKNHCKCLDS MSSGPATAAG TVASMLKEED PKDETSNQAP
ESVKDVKKPY VEKHHPKQTT FGISNDASKP LSWFEASKLP EEFSRHQIEV LQRTFIVKQF
LTRFERKQLA EKIGLNERQV RTWFQNRRRE EEDKQDGAQP KALREEQGWY EVAQEISDFS
KMMVPVALLI FLVCMIVFML TALFK
//
