ID A0A2G5UVQ0_9PELO Unreviewed; 725 AA.
AC A0A2G5UVQ0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Cni-Y46G5A.29 {ECO:0000313|EMBL:PIC43589.1};
GN Synonyms=Cnig_chr_II.g4268 {ECO:0000313|EMBL:PIC43589.1};
GN ORFNames=B9Z55_004268 {ECO:0000313|EMBL:PIC43589.1};
OS Caenorhabditis nigoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC43589.1, ECO:0000313|Proteomes:UP000230233};
RN [1] {ECO:0000313|Proteomes:UP000230233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT competition proteins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIC43589.1}.
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DR EMBL; PDUG01000002; PIC43589.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5UVQ0; -.
DR Proteomes; UP000230233; Chromosome ii.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd07828; lipocalin_heme-bd-THAP4-like; 1.
DR CDD; cd08544; Reeler; 1.
DR Gene3D; 2.40.128.20; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 2.60.40.4060; Reeler domain; 1.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR002861; Reeler_dom.
DR InterPro; IPR042307; Reeler_sf.
DR InterPro; IPR003582; ShKT_dom.
DR InterPro; IPR014878; THAP4-like_heme-bd.
DR PANTHER; PTHR24044:SF420; NEUROGENIC LOCUS PROTEIN DELTA; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF02014; Reeler; 1.
DR Pfam; PF01549; ShK; 1.
DR Pfam; PF08768; THAP4_heme-bd; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00254; ShKT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF50814; Lipocalins; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS51670; SHKT; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 331..367
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 368..407
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 408..443
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 445..481
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 484..521
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 357..366
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 397..406
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 433..442
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 471..480
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 725 AA; 82509 MW; 001BDEE5C390A1E7 CRC64;
MRLPRHLHGR PQTTDPPFDL SVFDSSGKRV ESYEVGKVYT VKLEAYVHFR GLLLQPRLCT
PNGAIIGTLR GGKFIEDEQF ETHGLIFHQC GRLVTNDSLT HTSDDKKFLA EAKWHAQHDV
GNVQFVATIA TENVLYWEKW RPKHAFLKGP YQKWSHQNPN IFVYNLEKEM EQKNTEKVVT
SEPITPSQHP LFEEQKEFLK GKMGTTVGTT VIPASLTETS ENSDDVFDFD GLAFESTGNP
GPVKFDKIQV TAASMMLAEK TDVTKNPEIS HSSKFLVEKP TESSFMMGRM FKKFAPLNDT
VLLEDDLKFL NAHAHHRRLQ HDFVDNNDLE MEEKCQDNPC ENGGRCSIQK GKIQCQCTPG
YTGQNCTEID KCIENECENN STCFNDKRSP VGYSCKCQNG TVGKLCEIQC PLDQCENGGK
CYLNTFGKIG CKCLPGTTGR RCEREINECG WNKCQNGAKC VDMFNDYRCD CADGWMGRNC
ERPCQDIYGS CRVWKREGQC DQMKNATDFF DINCAASCGI CNKIDNTTDT SYLPLQPILM
PFAFLLGEWK SQIKGWNNHT TDYPIDMEGM VYNETITFSV TPSLSFGTPY LNYTATMTNQ
DDPSNVHQYN GFLTIQQYKE NEESPDKGAL TTVSNTGIIM IEEGEILDEK SSTEGAPTLM
LTPTYQFFKF PVISGGNSNL KNPERSKRWF TLKNKRLMQY MVREFKGRTH KFTKIYKKTQ
EFKYL
//
