ID   A0A2G5VTD5_9PELO        Unreviewed;       963 AA.
AC   A0A2G5VTD5;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=SH2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   Name=Cni-gap-3 {ECO:0000313|EMBL:PIC55079.1};
GN   Synonyms=Cnig_chr_I.g506 {ECO:0000313|EMBL:PIC55079.1};
GN   ORFNames=B9Z55_000506 {ECO:0000313|EMBL:PIC55079.1};
OS   Caenorhabditis nigoni.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1611254 {ECO:0000313|EMBL:PIC55079.1, ECO:0000313|Proteomes:UP000230233};
RN   [1] {ECO:0000313|Proteomes:UP000230233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JU1422 {ECO:0000313|Proteomes:UP000230233};
RA   Yin D., Schwarz E.M., Thomas C.G., Felde R.L., Korf I.F., Cutter A.D.,
RA   Schartner C.M., Ralston E.J., Meyer B.J., Haag E.S.;
RT   "Rapid genome shrinkage in a self-fertile nematode reveals novel sperm
RT   competition proteins.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIC55079.1}.
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DR   EMBL; PDUG01000001; PIC55079.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5VTD5; -.
DR   STRING; 1611254.A0A2G5VTD5; -.
DR   Proteomes; UP000230233; Chromosome i.
DR   CDD; cd04519; RasGAP; 1.
DR   CDD; cd00173; SH2; 2.
DR   Gene3D; 3.30.505.10; SH2 domain; 2.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR19969:SF10; GTPASE ACTIVATING PROTEIN FAMILY; 1.
DR   PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   SMART; SM00252; SH2; 2.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF55550; SH2 domain; 2.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50001; SH2; 2.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230233};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          39..113
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   DOMAIN          131..192
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          168..288
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..329
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          363..385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        313..329
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   963 AA;  106888 MW;  6E60361D49C87324 CRC64;
     MLHHSNENNT PSASADGPPA IFSKSYDTRP ADISAEDVWY HGELNEHDAN HLLQGTTPGA
     FLVRQTGPTR FYLSILDNDG YPKHIPIRQL TTPHYFFEGK RYEKLREIVE AFKSAMFPIR
     KGGIMPLNGE IVEVKYLCVR HFEKRNSDEM TAEIGDILTL CETDEIGWMM GRNEANGSVG
     IVLKSHLEPL ISTVDNLSDL PYFYDTVTQE MLQFNPIGTF LLRRSSKGTD TYALLVKTQF
     DLIEKFLIVG SAPRGFSLAG RPFPTIGHVV ARYSERAISG GVRLTRAVCD GANEEQQQIR
     KASGRSATTE IRWPPPSEKT SIASMSSSQY DDVLKERKEK TRRMFRGASI DTALATSSAA
     TTSSTFLTPS GANSTSTAMP SPANTISTGV PEHMFDHHHG FNYEDINELS ETSSTSATTV
     ASTVALRKSR EEKQWKDCWL TLSDNPCGSS QLSVFDSQNS KLRQQLNLST CTMFWLDESV
     FSADGCLFLA PPFPSNQPTL YVCFRPFSTF LKWVRMLRSR TIYQDVPPPM LQGTISVGEP
     NSQVSFLSVE IDKYRLDSLK TEQFYSACVS VNGVKVGVSN SFAPAGNKGP SELPTVVIDS
     KFVIPCIPTC STNIQLSMLS HSSQTKKGRP CGTTVTVSLN ENNESVIQQS VDTSGFVFRA
     HRIRCPVLPL ERYRPMLDML RESPSQLLSW PSQVLPLHLK QFMYSCISHL YALSPQMMSP
     VIRKVIHDVL TTSTPEDVFR KDSLATGIIT QCLRHLFKTP FDEFLLENSQ FSQSLKSPDT
     AVELLVQFVD QRLLTIPLAS RLLVLAAECA RARFDGGDES HLVKRTLSAL LILRVLNPIV
     FSTLNNGIGS QIAKNVQISA NSAASQATNE SLTPAAMTIR RMFERLVLLV DQQPSTNTEN
     QYQSIIGSTS SEEIHTEWVS CLAYIIAHSL TIRPSGNATS STSSSEDVNL PISILELVRL
     HQM
//