ID A0A2G7FPM3_9EURO Unreviewed; 1229 AA.
AC A0A2G7FPM3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=AARAC_010640 {ECO:0000313|EMBL:PIG82558.1};
OS Aspergillus arachidicola.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=656916 {ECO:0000313|EMBL:PIG82558.1, ECO:0000313|Proteomes:UP000231358};
RN [1] {ECO:0000313|EMBL:PIG82558.1, ECO:0000313|Proteomes:UP000231358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117610 {ECO:0000313|EMBL:PIG82558.1,
RC ECO:0000313|Proteomes:UP000231358};
RA Moore G., Beltz S.B., Mack B.M.;
RT "Genome sequence for an aflatoxigenic pathogen of Argentinian peanut,
RT Aspergillus arachidicola.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIG82558.1}.
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DR EMBL; NEXV01000513; PIG82558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G7FPM3; -.
DR STRING; 656916.A0A2G7FPM3; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000231358; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd21691; GH2-like_DHX8; 1.
DR CDD; cd05684; S1_DHX8_helicase; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR049588; DHX8_GH2-like.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049621; S1_DHX8_helicase.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF85; ATP-DEPENDENT RNA HELICASE DHX8; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:PIG82558.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000231358}.
FT DOMAIN 260..331
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 575..738
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 756..936
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 118..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1209..1229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..187
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1229 AA; 138309 MW; 8D0B3817331DB466 CRC64;
MDDLQSLELF SLVSRITSEI QNHLGINDKT LAEFVIDQHL KCGSFSKFKE TLDEMGAEFP
QSLMESIDRL VLTMHPKYKT KKTDDADKVE GGDDMDVLDA LEKKARVFKG LAVPDKAPQW
DEDDYTDRKN ADEGDAKADA MDDTFAMLEG LAGKAREEKG RTTGEDRSSR KRSRSPGYDD
YDRGRRRKDK YRSRSRSHSP RYRKRDDDVD EFGRTRSKYS SRDEHRDGRS ERRQRRHDRS
QDDHFRKSPP VELDDAPILY KVYDGRVTGV KDFGAFVNLS GVKGKVDGLV HVSAMQEGAR
VNHPSDLVSR GQPVKVKVIS IQGSRIGLSM KEVDQVTGLD LIPQRRLASG ANMERLDGTP
ANDRYGNLSS DVPVIEDSNG RPMKNRKRLT SPERWEIRQL IASGVASAAD YPDLDEEYHA
TLTGEGTFEE EEDIDIEVRD EEPPFLAGQT KMSLELSPIR VVKAPDGSMN RAAMAGTNLA
KERRDLRQQE AQDKAAEQAA DVDLNAQWQD PMAAPEDRKF AADLRTAQQP KPDDAVPEWK
RVTMGKNQSL GKRTSMSIKQ QRESLPVFKF RKQLLDAVRD NQLLIVVGDT GSGKTTQLTQ
YLAEAGYGNN GIIGCTQPRR VAAMSVAKRV AEEVGCKLGA EVGYTIRFED CTSPETRIKY
MTDGMLQREV LLDPDLKRYS VIMLDEAHER TIATDVLFGL LKKTIKRRPD LRLIVTSATL
DAEKFSEYFN GCPIFSIPGR TFPVEIMYSK EPESDYLDAA LITVMQIHLT EPSGDILVFL
TGQEEIDTSC EILYERMKAL GSSVPELVIL PVYSALPSEM QSRIFEPAPP GGRKVIIATN
IAETSITIDN IYYVIDPGFV KQNAYDPKLG MDSLVVTPIS QAQAKQRAGR AGRTGPGKCF
RLYTEAAYQS EMLPTTIPEI QRQNLSHTIL MLKAMGINDL LHFDFMDPPP TNTMLTALEE
LYALSALDDE GLLTRLGRKM ADFPMEPALA KVLIASVDMG CSEEILTIVA MLSIQSVFYR
PKEKQQQADQ KKAKFHDPQG DHLTLLNVYN GWKNSKFNNA WCFENFIQAR QIRRAQDVRQ
QLLGIMDRYH HRIVSCGRNT TKVRQALCTG FFRNAARKDP QEGYKTLVEG TPVYMHPSSA
LFGKPAEHVI YHTLVLTTKE YMHCTTAIEP KWLVEAAPTF FKVAPTDRLS KRKKAERIQP
LHNRFAGEDD WRLSAQRRQG RGGGGGTWG
//
