ID A0A2G7G1W1_9EURO Unreviewed; 2141 AA.
AC A0A2G7G1W1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Polyketide synthetase PksP {ECO:0000313|EMBL:PIG86829.1};
GN ORFNames=AARAC_002933 {ECO:0000313|EMBL:PIG86829.1}, BDV24DRAFT_176958
GN {ECO:0000313|EMBL:KAE8346018.1};
OS Aspergillus arachidicola.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=656916 {ECO:0000313|EMBL:PIG86829.1, ECO:0000313|Proteomes:UP000231358};
RN [1] {ECO:0000313|EMBL:PIG86829.1, ECO:0000313|Proteomes:UP000231358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117610 {ECO:0000313|EMBL:PIG86829.1,
RC ECO:0000313|Proteomes:UP000231358};
RA Moore G., Beltz S.B., Mack B.M.;
RT "Genome sequence for an aflatoxigenic pathogen of Argentinian peanut,
RT Aspergillus arachidicola.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAE8346018.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 117612 {ECO:0000313|EMBL:KAE8346018.1};
RG DOE Joint Genome Institute;
RA Kjaerbolling I., Vesth T., Frisvad J.C., Nybo J.L., Theobald S.,
RA Kildgaard S., Isbrandt T., Kuo A., Sato A., Lyhne E.K., Kogle M.E.,
RA Wiebenga A., Kun R.S., Lubbers R.J., Makela M.R., Barry K., Chovatia M.,
RA Clum A., Daum C., Haridas S., He G., LaButti K., Lipzen A., Mondo S.,
RA Riley R., Salamov A., Simmons B.A., Magnuson J.K., Henrissat B.,
RA Mortensen U.H., Larsen T.O., Devries R.P., Grigoriev I.V., Machida M.,
RA Baker S.E., Andersen M.R.;
RT "Friends and foes A comparative genomics study of 23 Aspergillus species
RT from section Flavi.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; ML737117; KAE8346018.1; -; Genomic_DNA.
DR EMBL; NEXV01000221; PIG86829.1; -; Genomic_DNA.
DR STRING; 656916.A0A2G7G1W1; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000231358; Unassembled WGS sequence.
DR Proteomes; UP000325558; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 3.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR030918; PT_fungal_PKS.
DR InterPro; IPR032088; SAT.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR04532; PT_fungal_PKS; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF16073; SAT; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000231358};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 376..807
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1646..1722
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1764..1841
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1609..1646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1721..1764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2141 AA; 233944 MW; E20C41E6F56704CF CRC64;
MEGPRGVYLF GDQTSDFDAG LRRLLQVKNN TIVASFFQRC FHALRQEIAR LPPSERKIFP
RFTSIVDLLA RHRESDPNPA LESALTCIYQ LGCFINYYGD LGNVYPSASD CHIVGLCAGL
LSSAAVSCST NVGELLPAAV EAVVVALRLG LCVLRVRELV SSDQASSTSW SVLISGISEK
DASQLIGEFT AERAIPPSSK PYISAVGYNS ITISAPPKVL DDLIDSRLSK SHKPVRAQIH
GPYHAAHLYD GRDVDRIIES CHNEVVSNYT PRIPVLSSTT GQPIEAKQMK DLLKAALEEI
LLHQLCWEKV TDACSSILQT ARHQPCKLFP ISSTATQSLF TALTKAGITD IEVENGLGDV
PTNPKDNLNI SGRADCSKIA IIGMSGRFPE ADGTESFWDL LYDGLDVHRK VPAERWDVDA
HVDPTGTKRN TSKVPYGCWI NEPGLFDPRF FNMSPREALQ ADPAQRLALL TAYEALEMAG
FIPDSTPSTQ RDRVGLFYGM TSDDYREINS GQDIDTYFIP GGNRAFTPGR INYYFKFSGP
SVSVDTACSS SLAAIHMACN SIWRNDCDAA IAGGVNILTN PDNHAGLDRG HFLSRTGNCN
TFDDGADGYC RADGVGTIIL KRLEDAQVDN DPILGVINGA YTNHSAEAVS ITRPHVGAQA
FIFNKLLNDA NIDPKDVSYV EMHGTGTQAG DAVEMQSVLD TFAPDYRRGP GQSLHLGSAK
ANVGHGESAS GVTALVKVLL MMKKNTIPPH CGIKTKINHN FPTDLAQRNV HIAFQPTPWN
RPASGKRQCF INNFSAAGGN TALLVEDAPI AEVKGQDTRP VHVVSVSARS QSALKSNINS
LVKYIDEQGR SFNVNEADFI PSLAYTTTAR RIHHPFRVTA IGSSLQELRD SLNNSSRLES
FTPVPATAPG VGFVFTGQGA QHTGMGRHLY EKCSQFRTTM QHFDCISQSQ GFPSILPLVD
GSVPVEELGP VVTQLGTTCL QMALVNYWGS LGIKPAFVLG HSLGEFAALN TAGVLSTSDT
IYLCGRRATL LTEHCQVGTH AMLAVKASYP QVKQLLKEGV DEVACVNSPS ETVVSGLTAD
IDDLAQRCST EGWKSTKLRV PFAFHSAQVT PILERFQEEA QGVTFRKPSL PFVSSLLGEV
ITESNYDVLG AQYMVKQCRR SVNFLGALEA TRYAKLMTDK TVWLEVGAHT ICSGMIKATF
GPQVTTVASL RREENAWKVL SNSLSALHLA GIDINWKEYH QDFSSSHQVL PLPSYKWDLK
NYWIPYTNNF CLTKGAPQTA IQAAPQTTFL TTAAQKVVES RDDGTTATVV VQNDIADPEL
NRVIQGHKVN GAALCPSSLY ADIAQTLGEY LVEKYKPEFK DLGLDVCDMV VPKPLIAKGG
EQLFRVSATA NWAEKKASVQ VYAVNADGKK TVDHAYCTVK FFDTNASELE WKRISYLVKR
SIDSLHQNAE TGEAHRIQRG MVYKLFSALV DYDENFKSIR EVILDSDNNE ATARVKFQAP
PGNFHRNPFW IDSFGHLSGF IMNASDATDS KNQVFVNHGW DSMRCLKKFS PDVTYRTYVR
MQPWQNNIWA GDVYIFEGDD IIAVFGGVKF QALARKILDT VLPPVGGSKA PITAKPTPPA
RAQKANTGAK ARPKAPVPSK SFTKSSGPSV VVRALSILAS EVGLAESEIS DDMVFADYGV
DSLLSLTVTG RYREELNLDL DSSVFTDHPT VNDFKRLIAQ VSPSESHDGS SSEQESNFSF
NGGESSSAST PDITSPPNEK VAQVEQNDTM KEIRNIMAEE IGVPAEEIDP AENLGEMGMD
SLLSLTVLGR IRETLDMDLP GEFFIENQTL NDIEVALDLK PKTTAAPIPM PEPVKFPEAI
HDLQPKLAQH PKATSILLQG NPRTATKTLF LFPDGSGSAT SYATIPGISP DVCVYGLNCP
YMKTPEKLKC SLDELTAPYV AEIRRRQSKG PYSFGGWSAG GICAYDAARH LMFEEGEQVD
RLLLLDTPFP IGLEKLPQRL YGFFNSIGLF GEGKTAPPSW LLPHFLAFID SLDAYKAAPL
PFTDKKWAKK LPKTYIIWAK DGVCGKPGDP RPDPPTDGSK DPKEMVWLLN DRTDLGPNKW
DTLVGPENIG GITVMEDANH FTMTKGEKAK ELSTFMANAM A
//
