ID A0A2G7G8R1_9EURO Unreviewed; 1577 AA.
AC A0A2G7G8R1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Guanine nucleotide exchange factor {ECO:0000313|EMBL:PIG89212.1};
GN ORFNames=AARAC_008663 {ECO:0000313|EMBL:PIG89212.1};
OS Aspergillus arachidicola.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=656916 {ECO:0000313|EMBL:PIG89212.1, ECO:0000313|Proteomes:UP000231358};
RN [1] {ECO:0000313|EMBL:PIG89212.1, ECO:0000313|Proteomes:UP000231358}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 117610 {ECO:0000313|EMBL:PIG89212.1,
RC ECO:0000313|Proteomes:UP000231358};
RA Moore G., Beltz S.B., Mack B.M.;
RT "Genome sequence for an aflatoxigenic pathogen of Argentinian peanut,
RT Aspergillus arachidicola.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIG89212.1}.
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DR EMBL; NEXV01000073; PIG89212.1; -; Genomic_DNA.
DR STRING; 656916.A0A2G7G8R1; -.
DR OrthoDB; 5476208at2759; -.
DR Proteomes; UP000231358; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000231358}.
FT DOMAIN 379..507
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 1331..1574
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 727..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 873..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1050..1072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1096..1208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1072
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1577 AA; 174307 MW; 58BDA2B2482B7E04 CRC64;
MEPNMSLVES PGGKPGHAQG KSITALLERN FGSNTLSSLE DKNATCTLRR AHTVAQGKNV
GEKTKVGSKT ARERIATSFL RVKDSHELLR KRSSKRLDAP ASPRDTPAAA REPNHFTVGN
VGQNGKIFLR PIRNQSLKEP RPQPFASSVD QSKGEYVHSR GLDGHGVDEP SRWSNSQLSE
LRPELIPEET CDDGQSIKTE STRSGPYRFL RRPRPRARSF STISEQGSTL RAGANGEFRI
FIERSEDRPK SADGSLRPTL GTSIPHYGWD FSYYGADGST PLYNSIYSRA SLSDNFLAAR
FLRESLNPGP TSDVYLSQPD RPSFAASMFS GTPAIELTRG STATDKPILY ELKEPIEPSI
FENLVSQMDD DTVVRYVPRT KDISAASPAR IVAQISSESF MDYELVSDFF LTFRSYLSAS
SLLALLLARL QWAINRLQDD GRIIRIRTFA ALRHWILNYF VDDFIPDFDL RVRFCETINR
MYDNVKAREG GGTSDLKILI DLKRCWYGRC SAYWDFQDQH IAYHTPDYLI VPGGDEQLAT
SCAESQLRMV RTTSGQDREG RPRPPHVRND SSATAKSMPV SVDSDRSIHA TSCSLPPKSP
KRLSMAIMDT KGPHPVPLAP LKPVGSLQGP PTSSPVTSRR FPFHSHAHKR SGSFSDSARD
GRAPLSLLKL DSQGNLLAPD ALNLGSLIRG ELYAPAESQP EETTKPATSS SGVKTIIGSI
RRALNGRNVG QGTSTRNTNG PFAPSTRGKT SAMPTNVAFG SDYYRDRKAA TAAKKPTKID
ILCDRSLQQY HRALTGYADA KEGDPVQEAG TLRSRRSWLA GVDVDELDHP VLRPDQGRAK
SVLTGGSKSI VIVDDTGLRS PLISLSRASQ SLRPPGLFAS QRSSSVGRGS TSWKRTSPSL
RLRKYASFQS GISRQRLAVV AEPDLPSLDQ GSPGNLEKPA GPTLRRRPGG DLRQMRDGLG
SPLRSHPASF VSNTTYRSST AGSGATYATD VHSRPQTHLI PPNPRFSLLQ THSSQDLRRS
FEAAIAQFAQ IPDDDDGGVE SALMKLEGKW TGGSTDTAAE PQQSTQVQGS VREQEFYHAH
TRAVWDAGVH RRQTLASESS TYSHFRGRSV PRRPYSESLA ESEDSYSSIP LLERGLSDES
MKKPSQSRAS SHQAAPGRVQ PSDASSKYTW DTESSHPSFD IVKETESIKR IPRGSTFPAP
HGLSNRLSGL SEDSADLIDS HEAVDQRLSL YTDSMSRSSL GIPRHPLAHP PTPPMTIQHR
SVASCASPLN PALFQAPPLT PDPSPSRNIE PVHVRAIDTQ HVSSDVLSQS EWDRQYQYPE
PDHVPFILSC ESQTLAQQMT IIEMAALSEI DWKDLVDMRW SSGSPSSVSW VQFLMEEERR
GIDLVVGRFN LMVKWILSEI VLTRNIHERA RTITKFIHTA AHARRMCNYA TMLQIAIALS
STDCSRLQKT WGLVSSEDRG LLKDMEVLIQ PVRNFHDLRV EMETANVQEG CIPFVGLYVH
DLTYNSQKPA QVAAHGGEPL INFERYRTTA KIVKSLLRLI DASTKYTFAP VQGIIERCLW
IASLSEEEIQ THSKQLE
//
