ID A0A2G8EHU3_9GAMM Unreviewed; 758 AA.
AC A0A2G8EHU3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:PIJ74083.1};
GN ORFNames=BK416_04795 {ECO:0000313|EMBL:PIJ74083.1};
OS Erwinia sp. OLSSP12.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=1912096 {ECO:0000313|EMBL:PIJ74083.1, ECO:0000313|Proteomes:UP000229786};
RN [1] {ECO:0000313|EMBL:PIJ74083.1, ECO:0000313|Proteomes:UP000229786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLSSP12 {ECO:0000313|EMBL:PIJ74083.1,
RC ECO:0000313|Proteomes:UP000229786};
RX PubMed=29067021; DOI=10.3389/fmicb.2017.01969;
RA Chen X., Hitchings M.D., Mendoza J.E., Balanza V., Facey P.D., Dyson P.J.,
RA Bielza P., Del Sol R.;
RT "Comparative Genomics of Facultative Bacterial Symbionts Isolated from
RT European Orius Species Reveals an Ancestral Symbiotic Association.";
RL Front. Microbiol. 8:1969-1969(2017).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIJ74083.1}.
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DR EMBL; MNCH01000011; PIJ74083.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8EHU3; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000229786; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:PIJ74083.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:PIJ74083.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000229786};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..145
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 140..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 84105 MW; 863717EEEA54ABCD CRC64;
MLNQELELSL NMAFARAREH RHEFMTVEHL LLALLSNPSA REALEACTVD IVALRQELEA
FIEQTTPVLP AAEEERDTQP TLSFQRVLQR AVFHVQSSGR SEVAGANVLV AIFSEQESQA
AYLLRKHEVS RLDVVNFISH GTRKDETNPQ QGSENPVNEE QAGGEERMEN FTTNLNQLAR
VGGIDPLIGR DKELERTIQV LCRRRKNNPL LVGESGVGKT AIAEGLAWRI VQGDVPEVMK
ECTIYSLDIG SLLAGTKYRG DFEKRFKALL KQLEQDNSSI LFIDEIHTII GAGAASGGQV
DAANLIKPLL SSGKIRVMGS TTYQEFSNIF EKDRALARRF QKIDITEPSV EETVQILNGL
KPKYEAHHDV RYTAKAVRAA VELAVKYIND RHLPDKAIDV IDEAGARARL APASKRKKTV
NVADIETVVA RIARIPEQSV SATDRDTLKN LGERLKMLVF GQDNAIEALT EAIKMSRAGL
GHERKPVGSF LFAGPTGVGK TEVTVQLARA LGIELLRFDM SEYMERHTVS RLIGAPPGYV
GFDQGGLLTD AVIKHPHAVV LLDEIEKAHP DVFNLLLQVM DNGMLTDNNG RKADFRNVVF
VMTTNAGVRE TERKSIGLIH QDNSTDAMEE IRKVFTPEFR NRLDNIIWFN HLSTAVIHQV
VDKFIVELQA QLDAKGVSLE VSDDARAWLA EKGYDKAMGA RPMARTVQDN LKKPLANELL
FGSLVNGGSV SVALDKEKNQ LTYHFLSAEK RKAEGTVH
//
