ID   A0A2G8JCL2_STIJA        Unreviewed;       327 AA.
AC   A0A2G8JCL2;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Target of rapamycin {ECO:0000313|EMBL:PIK33482.1};
GN   ORFNames=BSL78_29702 {ECO:0000313|EMBL:PIK33482.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK33482.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK33482.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK33482.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK33482.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK33482.1}.
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DR   EMBL; MRZV01002529; PIK33482.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8JCL2; -.
DR   STRING; 307972.A0A2G8JCL2; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024585; mTOR_dom.
DR   PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR   PANTHER; PTHR11139:SF9; SERINE_THREONINE-PROTEIN KINASE MTOR; 1.
DR   Pfam; PF11865; DUF3385; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT   DOMAIN          237..327
FT                   /note="Serine/threonine-protein kinase mTOR"
FT                   /evidence="ECO:0000259|Pfam:PF11865"
FT   REGION          284..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..310
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   327 AA;  36019 MW;  C09B12983F977D02 CRC64;
     MRTFSSRGNQ PSSLENGDIT NIVLALRTLG SFDFEGHSLT QFVRHCADNF LSSEHTEIRK
     EAAWTCSRLL QPSINLRSTS SPSTGSTNTQ VVADVLSKLL VVAITDSAQA ENLSALFVAL
     NDEQFDIREL AMCIIGRLSN LNPAYVMPSL RKTLIQIMTE LEHSGVGRNK EQSAKMLCNL
     VSNAPRLIRP YMDPILKALI PKLKEADPNP GVIINVLKAI GEQSQVSGVE MRKWMDELLP
     ILIDMLQDSS SLSKRENALW TLCELTIRAL GLLGALDPYK HKINQGKKDS MTDTAAALST
     SETKTSQEAS EMLVTLGSPN LEDFYPQ
//