ID A0A2G8JCR8_STIJA Unreviewed; 191 AA.
AC A0A2G8JCR8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE SubName: Full=Echinoderm microtubule-associated protein-like 5 {ECO:0000313|EMBL:PIK33537.1};
GN ORFNames=BSL78_29647 {ECO:0000313|EMBL:PIK33537.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK33537.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK33537.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK33537.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK33537.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- SIMILARITY: Belongs to the NPC2 family.
CC {ECO:0000256|ARBA:ARBA00006370}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK33537.1}.
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DR EMBL; MRZV01002506; PIK33537.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8JCR8; -.
DR STRING; 307972.A0A2G8JCR8; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0032934; F:sterol binding; IEA:InterPro.
DR GO; GO:0015918; P:sterol transport; IEA:InterPro.
DR Gene3D; 2.60.40.770; -; 1.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR003172; ML_dom.
DR InterPro; IPR039670; NPC2-like.
DR PANTHER; PTHR11306; NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED; 1.
DR PANTHER; PTHR11306:SF73; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2; 1.
DR Pfam; PF02221; E1_DerP2_DerF2; 1.
DR SMART; SM00737; ML; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT DOMAIN 42..163
FT /note="MD-2-related lipid-recognition"
FT /evidence="ECO:0000259|SMART:SM00737"
SQ SEQUENCE 191 AA; 20522 MW; B7569C9B58A42F8E CRC64;
MKVLFGLDIT KMKDTFIVVF ILASFCLYGN VQAEIRKNIP DFLDCGSVGA KVTSVDLTPC
SSDPCTVISG KKSSIAVSFH TTAVATNVTA KVYGSIASVK VPFPLPQADA CQKSNLTCPL
KAQADYVYTC TLAIPGHLPE VDVVVELDLV VDDKKYLCIE FPVSVKPSSS KVFQKIKAIV
EDVELIPADL S
//
