ID A0A2G8JF34_STIJA Unreviewed; 613 AA.
AC A0A2G8JF34;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=BSL78_28823 {ECO:0000313|EMBL:PIK34352.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK34352.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK34352.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK34352.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK34352.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK34352.1}.
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DR EMBL; MRZV01002203; PIK34352.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8JF34; -.
DR STRING; 307972.A0A2G8JF34; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46167; N-LYSINE METHYLTRANSFERASE KMT5A; 1.
DR PANTHER; PTHR46167:SF1; N-LYSINE METHYLTRANSFERASE KMT5A; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 24..146
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 197..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..486
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 67292 MW; B5ACFE199CF8B7E5 CRC64;
MRRKRREKPE DVAISMVKRK TDRDGFYVKE IPQKGRGVFA KVKFTKGEFL LQYAGSLLSV
NEGDKLEEEE GSSGFRFFIS CKGKEFCIDA TEERETGPIL GRLVNHGEKN EVNVKPSILD
FEGTPVICLF ALTDIAEGEE LLYDYGVSNL PWKQQAKAHN ENGSTSSVAT GISASLKKDI
LSSLEKRVSD QHSELISSVI DTEDSPESNA STSDPTPMTE SEQNEKESSS PTKISAEGLE
TFSLVMDTKE PSYGDVSTSD SQPMNANEQN EERSSSQEKD ISTIGTKISS SVMHTEDPSN
SNALNSDPQP MTVSERNKKG SSSPDKDITV EGPEICSLLM DPEDPSDSSA LTSDSQPMTA
DDMKFAPKIL MKETPMKHTE VSSLVLNLET ENVLKDASQL LNEKSPLSLE KYMSDIGSEI
CSLIMDTEDS LECNASTIDS QLMTQDIPAK GPETCSLVMD NEVSESDAST SESESESSHS
DDYVPESDYS EDGESYVIPL PRFTQRSGCV SSSSSRKCSS HNTKQNCEEE TDCVSSSSDI
INQCSQEKTS CNSASSSRSC GIQVLQTNNG RKRKYDKSAY CPFCQTSQAK LPRHLSEFKE
HKDEPEVYSM AGN
//
