ID A0A2G8JH57_STIJA Unreviewed; 756 AA.
AC A0A2G8JH57;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BSL78_28094 {ECO:0000313|EMBL:PIK35080.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK35080.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK35080.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK35080.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK35080.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK35080.1}.
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DR EMBL; MRZV01001993; PIK35080.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8JH57; -.
DR STRING; 307972.A0A2G8JH57; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16584; RING-HC_TRIM56_C-V; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF229; NHL (RING FINGER B-BOX COILED COIL) DOMAIN CONTAINING; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 17..59
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 94..141
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REGION 237..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 322..360
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 239..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 86544 MW; E1878E0F846B9F53 CRC64;
MASSSPLKDM EKNFFRCSVC LDQLKNPKLL PCLHRYCSDC LKVVIQISDT ETFKCPMCNQ
HHAIPANGVD GFKTDFHMKS MLEFIQLQNS FKEKELKKCI SCSQKKTVTA YCFKCKNFLC
DPCYHFHIKN PMFIDHQPHT LNLESYEEQN LTLEKLAALT EDPRCHLHVK QQAQLCCCTC
GNVPVCVTCT YSKHKGHDLH DVTELAKTER EALKFKMATL NEFDRKASDL RNKLQSTSRR
LRDNVASKST QLTNQHKQQV NKIQYKIDEN TSERERGLKD IETRRNCEIC QIRKKREDEL
CRVREKYNAI ICDAGEIYDK ETNKLRAKYD EIESALSRML ERLNNQVKGL HETKVQQTIQ
NETELTKLSD YCEQIIKRYE NFRATATSIL ACNNEWTDAQ CIPDIRRACE PLTEEIDRGF
PGLESLSDVA MGDLTKVIVD DVRLTELEET VVDVEGIKAK GWRNTSMTST SEGEIVITGK
LSGDRSHITV INKDGKTQIQ KQVRREKNCS EYPYRYCSYL SDAIVVTVCK ADEMGVFNVR
SGSYEKKMIS DVTNSWPADR CVTCICTDRA TNRVIVGTNT RDLYVFDNQL NFSHIIKLPE
EINHSADIAL HRGNLLVCDA EGMEAYAIST EESTAKLLYK FVKPRLDGIN WRPLRVCTDK
NGFVYMLWTA FSSGLWRCLL LQYSENGQQL LTTRIVDGNA RCLATLEIGG NEKLLITTVH
SGKLYTYGLV VKSLINYYDA TSKRSATTDE NYLCVS
//
