ID   A0A2G8JMZ4_STIJA        Unreviewed;       674 AA.
AC   A0A2G8JMZ4;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Putative receptor-type tyrosine-protein phosphatase alpha {ECO:0000313|EMBL:PIK37088.1};
GN   ORFNames=BSL78_26079 {ECO:0000313|EMBL:PIK37088.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK37088.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK37088.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK37088.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK37088.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK37088.1}.
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DR   EMBL; MRZV01001561; PIK37088.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8JMZ4; -.
DR   STRING; 307972.A0A2G8JMZ4; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd00047; PTPc; 2.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR19134:SF477; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR   PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR   Pfam; PF00102; Y_phosphatase; 2.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 2.
DR   SMART; SM00404; PTPc_motif; 2.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 2.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE   4: Predicted;
KW   Receptor {ECO:0000313|EMBL:PIK37088.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT   DOMAIN          136..393
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          311..384
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   DOMAIN          418..673
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          596..664
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          66..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   674 AA;  76893 MW;  D5185928CCDED674 CRC64;
     MNKSPTKKLD LKLIPGVTAD PGDYIALEER SRNTIHETAD AAPNAMPRQG IKSHTDYQHE
     DVNFGETDAR KLPSVPHPDL QSEDDTEYEV PEMFEEYTGV YINTLRVSKP ITPRPMKITE
     YKTFMGRERS KVIREIVQQY TALKTGQQHP WTAAVKLQNK PKNFFKALLP YDHSRVRLDT
     DGSDVRSDYI NASYIKNHQG KVSFIAAQGP REGTKDDFWR MVWKEDVETI VTLVDKDGTD
     QHSKDAQYWP NKVNTSQKYG AITVLLMEKT AFRSYTLREM NVIKGNEKFH TTVTQYEIPC
     WKYGGVPSEP ADLISVIKQI KNHQKGSKHL LVHCSNGVGA TGVFISLYDL MDVIKTKKEV
     SVFDVIEGMR KDRVNMVLTK LQYLFIFDAL LEAMLSPDSQ MSCDQLKKLD LSAMKKKCKK
     EFQILQETTK HQEDLATLAG NSSENNHKNR FPDLLPVDKF RPVLKSPGNL FGSNGYINAT
     FAKNISQRGF IMTQSPLAST VEDVWRLVFD YGCKCIVMLN TVDDSDESLT VYWPNVHNAA
     ASNGLMTVIC RKIEESDVFT RRQFEVKHKR SQKALLVDHF SFHGWLGNKP DVHKLREFIK
     YTRTKGTGPA LVHCINGVGL SAVYVTVISE LERIDKEGTV DVFQTLNKLR KQCPKAVQTQ
     DEYLLCYELL RDHL
//