ID   A0A2G8JSC1_STIJA        Unreviewed;       274 AA.
AC   A0A2G8JSC1;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Solute carrier family 23 member 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BSL78_24511 {ECO:0000313|EMBL:PIK38662.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK38662.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK38662.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK38662.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK38662.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK38662.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MRZV01001331; PIK38662.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8JSC1; -.
DR   STRING; 307972.A0A2G8JSC1; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR11119:SF118; SOLUTE CARRIER FAMILY 23 MEMBER 2; 1.
DR   PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        175..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   274 AA;  29605 MW;  4AE02B239FB8AE43 CRC64;
     MIAGILASMV ESIGDYYACA RISGAPPPPE HAVNRGIGME GFGSLLAGMW GSGNGTTSYS
     ENIGAIGITK VGSRRVVQVG ATIMLFLGVF AKFGALFVTI PDPIIGGMFC TLFGVIAAVG
     LSNLQYVNLQ LYLFGFPVIY GLCDTDVHSD QPHQHKLNFK NTWLKLRDSE GFNQIATVLL
     STNMFVGGVL AAFLDNTIPG SAEDRGLTKW RKMFDEGSSS SRSEILKCYD FPVGMKWVES
     VRFFKYIPFC PTFGGWGFKK LLTRGPASGS SGEF
//