ID   A0A2G8K3E4_STIJA        Unreviewed;       212 AA.
AC   A0A2G8K3E4;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 9.
DE   SubName: Full=Putative A disintegrin and metalloproteinase with thrombospondin motifs 6 {ECO:0000313|EMBL:PIK42527.1};
GN   ORFNames=BSL78_20603 {ECO:0000313|EMBL:PIK42527.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK42527.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK42527.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK42527.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK42527.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK42527.1}.
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DR   EMBL; MRZV01000926; PIK42527.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8K3E4; -.
DR   STRING; 307972.A0A2G8K3E4; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   PANTHER; PTHR11905; ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN; 1.
DR   PANTHER; PTHR11905:SF159; MIND-MELD, ISOFORM J; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Integrin {ECO:0000313|EMBL:PIK42527.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        185..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          32..125
FT                   /note="Peptidase M12B propeptide"
FT                   /evidence="ECO:0000259|Pfam:PF01562"
SQ   SEQUENCE   212 AA;  24520 MW;  2DCA0A581B9A5752 CRC64;
     MLMNYYSLQR LQELAITASF DDKLIQQFGH YELVVPSLVN HRGDFLSYDI INSRKRTRRH
     LDTHKEPLAD KTIHYSVQAY GTQFHMNLTL NTKLISPHFV VEREDRTGVV SSHRYVDDCH
     YTGHLFGHQR SSIAVSNCRG LHGLMKTADE EYFIEPLDQY SSTNLYSEGH PHIVIKDLPY
     QGRRIYNIII IIIIIIVKMP VIPVVVCLVS PV
//