ID   A0A2G8K478_STIJA        Unreviewed;       303 AA.
AC   A0A2G8K478;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000256|ARBA:ARBA00020594};
DE            EC=2.1.1.60 {ECO:0000256|ARBA:ARBA00011914};
GN   ORFNames=BSL78_20330 {ECO:0000313|EMBL:PIK42817.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK42817.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK42817.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK42817.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK42817.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK42817.1}.
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DR   EMBL; MRZV01000901; PIK42817.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8K478; -.
DR   STRING; 307972.A0A2G8K478; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0018025; F:calmodulin-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR025800; CaM-Lys-N-MeTrfase.
DR   InterPro; IPR019410; Methyltransf_16.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13539; CALMODULIN-LYSINE N-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR13539:SF3; CALMODULIN-LYSINE N-METHYLTRANSFERASE; 1.
DR   Pfam; PF10294; Methyltransf_16; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:PIK42817.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PIK42817.1}.
SQ   SEQUENCE   303 AA;  34429 MW;  1183C66CA397EE81 CRC64;
     MKNADEKSNV RKKAIAKSRW KLIYKALKNE AATSSTDENV SVMRFKSFGF LQQKSLPEMT
     GSEDVMWSQI SFDESHEYSL KIRQLNMKLS AQDLIGFNNT GNVCRSKSVC ELGGGMTCLA
     GFTVACTSNA KEVLVTDGNL KSCQNAEIIA KENHSKFGTT EVSVRQLLWN KPETFADLKE
     KFDIVAGADW IQIRATINNN NLRRDEMYLS CFVAFSLMTT DRICQHIKHI LKPEGIAWMF
     APQRGSTLKK FQEIAEADFT IELQENYDSD VWAKHQKLNS SVGDAGHYDE DIHYPWLMIL
     QNR
//