ID A0A2G8K7B3_STIJA Unreviewed; 518 AA.
AC A0A2G8K7B3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative NADPH oxidase 5-like {ECO:0000313|EMBL:PIK43894.1};
GN ORFNames=BSL78_19224 {ECO:0000313|EMBL:PIK43894.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK43894.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK43894.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK43894.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK43894.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK43894.1}.
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DR EMBL; MRZV01000815; PIK43894.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8K7B3; -.
DR STRING; 307972.A0A2G8K7B3; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0019722; P:calcium-mediated signaling; IEA:InterPro.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR045198; CNBL1-10.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23056; CALCINEURIN B; 1.
DR PANTHER; PTHR23056:SF143; CALCINEURIN B-LIKE PROTEIN 8; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 204..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..81
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 82..117
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 134..161
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 479..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 58413 MW; 91F63E850EA1DA04 CRC64;
MPVKWGQASM DEDAKWLQRF EKKFHHYSGE DNLIQLDEFI QVLNIKESFF AERFFEFVDQ
DKSGSISLKE LLTALRLLIN GKPTDKLHFL FKVYDVDGNG SIDFEELRTV LRFCMAESAL
SLSEDILCEL TEVLFEDADT DGNGKITFEE LRNQLDRYPD IASNLTISAA EWLKPPRRSA
RGNDNINLYF GKLFKTIRLL SNNLSTVFLL VIFFSINIAC GVWGVMDVYT TTPDKPWLML
ARFNGRPLNF NCSFILVLML RKSLTWLRST RLAAILPVDQ HVTLHKLVGI VVVLEAFLHA
VGHFGNCADL IIQNTTEYTA WEILFTQASG IGWVAALAFP TEYITVHIRA QGNWTKRIFN
FVKKYNNEKV GIRKESQRLE ALIEEGSPSG SNTNNLKCTS VVSVLRNENE TSIHGTPATV
RNIAVLSKDD DRFAVTNFSA KYDTKEDLTS NRSSELYGSS PNGWMKSEIV VDDRKALLSR
ASSKSGSSSN SNNDLTASSS AARSHGTLPE LRGHHPWP
//
