ID A0A2G8KAX9_STIJA Unreviewed; 2016 AA.
AC A0A2G8KAX9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=Putative MAM and LDL-receptor class A domain-containing protein 1 {ECO:0000313|EMBL:PIK45151.1};
DE Flags: Fragment;
GN ORFNames=BSL78_17991 {ECO:0000313|EMBL:PIK45151.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK45151.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK45151.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK45151.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK45151.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK45151.1}.
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DR EMBL; MRZV01000731; PIK45151.1; -; Genomic_DNA.
DR STRING; 307972.A0A2G8KAX9; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd00112; LDLa; 3.
DR CDD; cd06263; MAM; 11.
DR Gene3D; 2.60.120.200; -; 12.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR23282; APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR; 1.
DR PANTHER; PTHR23282:SF101; RT07201P-RELATED; 1.
DR Pfam; PF00057; Ldl_recept_a; 2.
DR Pfam; PF00629; MAM; 12.
DR PRINTS; PR00261; LDLRECEPTOR.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00137; MAM; 11.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 12.
DR SUPFAM; SSF57424; LDL receptor-like module; 2.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 3.
DR PROSITE; PS50060; MAM_2; 12.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Receptor {ECO:0000313|EMBL:PIK45151.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT DOMAIN 1..160
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 162..276
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 276..412
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 420..574
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 576..736
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 739..900
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 922..1078
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1080..1243
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1245..1410
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1450..1608
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1653..1817
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 1876..2016
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DISULFID 1434..1449
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1615..1627
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1622..1640
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1634..1649
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1841..1853
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1848..1866
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1860..1875
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PIK45151.1"
SQ SEQUENCE 2016 AA; 221736 MW; CE60D2F1F813F179 CRC64;
ANCTFELGTC GYYQLKDDDF DWTRKAGTTS STNTGPTSDH TTGTGYYMFI ETSSPNLLGW
KARLALHPQR PTDDAGLCLI FYYHMFGDTI DTLNVILATG TQEDVIYTRS QSQGNQWRKA
QVPVKTASGW QVIFEASRGT SFTGDIAIDD VFFFPGECPQ TSSCTFESGF CSWTQDGLDD
FDWSLGSNGV ITQGTGPATD FTTGTNLGVF IYANNQLPRT FGEISRLYSP LVQDTLGSSC
LTFYYILYGK DVGAISVFYY DIIADQINGP VWEQFGFCDF EEQLCSWENS VGDDEFDWIQ
NRGTTSSSGT GPSVDHTYGN SLGFYLYIET SSGTTGYKAR LNSRYYPASN GEFGCITFWY
HMYGATVGTL RIQLKDEDGK LTEIIIEGVR GTSTTGDIAI DDVDVSDEVC VNAPGGDRGL
DCTFDLDICS YAQVTGDEFD WEVGVDAVNG PLYDRTTGSG SYAYINMGQT HNAGDRARII
SPLQAPSAGG ACLSFWYHMS GINIDRFAVY LRADDSDSIV FTRTGTQGDE WIRGEKTIQM
DTAWQVLFEG RYSTNDMGHI ALDDVILSGS PCTADFECDF ETDLCGWTQG TTDNMDWTRY
KGTTPSTGTG PTTDHTTGTA EGYYIYLETS VGSSNYKAQL YSPQYSYTDG DCFTMWYHMY
GATINALNVY SYDVLTEEQN TLFSRRVTSI NEWRYTTMTV TARHSYQIIL EALRGSSSTG
DIAVDDIRLT PGPCPGTPGY CDFESGFCTW LNDRSSDVWD WDRTRGLAGQ SYNPGTDHTT
NTGYGFYMSF PILPPTVAQG DNAILISEYM SPVSDACFKM WYHMTGSGTG TLTVTARGTS
GSYTIGTLTG DAGNVWKYLT RSVTQKVEFR IFIEATSDSA KGSGHVAIDD VDMEPVSCSS
LTTPQPTQAA STVGPTQPVG IYDCSFEDGF CLWQQDPSNQ VDWERTLGTT SSSDTGPLGD
HTTGGLLGFF IYVDSSGQYN TFGRIVSPEM TSTSVGKCVR FWYNMYGSDV NTLNMIQRKS
ALDTVMWTKT GNQGQVWLLG QAHLTGTFQA IFEVVTSSGT RGDIALDDIS FWDTECPSPD
ICDFERGPGA CDLTQDGTDE YDWSWTNGAA GNPFDDSRPE KDHSAGTNQG YYFLFNETTP
TLIRDNDASF FSKTLSPGEL CLQFWYRTSG FQAKLDVYSE LNGNSVPIGT FSKVETSSGR
WHLGQVKVNY GIEYRIRFTG VLRLDDLYVA IDDIDFSKLF CSDLGSTNFE DGFGTYANIE
DDEFDWIRQA GSSPNQNTGP SSDHTLSTEF GFYAFIDTSA PRSPGDRAWM VTDTNIDIGR
PFCMSLWYHM YGPTPGTLTL YQRGNEADYR DWRAIQSWTG DKGDYWNGVI VDIAALNPLI
QLVFEGMVGE GNQGDIALDD IQLYAGRCVA PTLPPCVFEC DAGTLCLSDV GQICDFVADC
EDGTDEALCG ACDFENGLCG FQELSSGSYR WMNSTGATPT ENTGPEADHT LGTDEGTYMY
VDASSGSGYS KALLRTPDLY ESAPGCLLTV WVHIQGTDIG ELGIYIIRDT IRTLLLLIPD
PLGQEWVQIQ VGVGRIVGQF QIQFEAVRSF SVLGDIALDD VSFSGCSFPE SEAVCRNDEF
RCDSRGCIDN SRICDLTDDC GDNSDEAVCA GYTSCTFEYG LCSWQQLVND ELDWYRITSG
TPTAWTGPER DHTTGLATGH YLYLESSSPR KPGNRARLGS INLRASGGDC EIRFFYHMFG
EDIGSLNVYK RKVINGPLTL LWSRSGNLGD FYERADVVVA NSTDYDVFQV ILEATVGDGI
YGDIAIDDIT FTDSCQVRNE TQLPEMTTLP PVSVMTTQRP CQKGDFICTS GFCLPIDVRC
DGTADCADGS DEQDCGNCDF ENSQCGWQAI PSGLYIWQRQ LARDAPASIA PGNDHTTLSP
AGYYMYVDQT QGTFGLAAVL QSPSLLGNTG TRCQLEYWYH MYGGEAGALV VNLYENLIPV
SSKSYVGNQG QQWLKGTCDV GAKAVGQYYV RQDLRS
//
