ID A0A2G8KDW1_STIJA Unreviewed; 713 AA.
AC A0A2G8KDW1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE SubName: Full=Putative Fanconi anemia group J protein-like {ECO:0000313|EMBL:PIK46155.1};
DE Flags: Fragment;
GN ORFNames=BSL78_16976 {ECO:0000313|EMBL:PIK46155.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK46155.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK46155.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK46155.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK46155.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK46155.1}.
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DR EMBL; MRZV01000662; PIK46155.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8KDW1; -.
DR STRING; 307972.A0A2G8KDW1; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT DOMAIN 65..324
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PIK46155.1"
SQ SEQUENCE 713 AA; 80459 MW; BDEC4B5DB0597171 CRC64;
KNSSSHSMMC LLEEGEQDTL SKDLPQDGLA STSDKPTVDN VTTTKNDDDD SDIFQTDQIK
FRTPGSKARA KQCTDEDEEP SKSRCVATDR KTTSGEKLLG VSCSCACHSL DKPCMGATDE
AEPIRLPKIY FGTRTHKQIA QIIRELKRTA YSEVKMAILG SREHLCVHPE VSRSKNKNDG
CRELLDTKTG ISCRYYANVQ KIKHHWQLEG HGLTSAWDVE DLVKLGKKIK SCPYFATRSL
ANDADVIFCP YNYLIDPLIR SSMDITLKDQ IIILDEAHNI EDSAREAASA TIRADELQDV
MDELDKLIQY KWREEHCRAM HVVAANLQRW IASQSGSLSQ NDFNKASKVW SGVEMVAQFN
NMGVSPGTFD VLKHHLAALF EEPNPQIPVE EMMSLTSASG MLLRGLFIIV DYFFRENMVY
MKDYKVVMIK EFSQRKGRDN TDNRWLNPRR GSSERLTYSL NFWCMNPAVA FSDVGGEART
IVLTSGTLSP MGSFASELGV EFSISLEANH VIKDSQVWVG SIATGPTGKT LNASYRNTET
FNFQDDLGRL VLDVCKTIPF GVLCFFSSYS LMLKLSERWK NTRLWSEISE KKIIMTEARG
GMKKEFDEQL KEFYSTIEDF ESSGIEDRTV TGVLFLAVCR GKVSEGMDFA DNNARAVITV
GIPFPSFKDP QVELKRAYND QNRDRGLLSG SEWYEIQAYR ALNQALGRCL RHR
//
