ID   A0A2G8KFU6_STIJA        Unreviewed;       232 AA.
AC   A0A2G8KFU6;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=Guanylate cyclase {ECO:0000313|EMBL:PIK46874.1};
GN   ORFNames=BSL78_16248 {ECO:0000313|EMBL:PIK46874.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK46874.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK46874.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK46874.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK46874.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK46874.1}.
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DR   EMBL; MRZV01000616; PIK46874.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8KFU6; -.
DR   STRING; 307972.A0A2G8KFU6; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR44755:SF11; ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1; 1.
DR   PANTHER; PTHR44755; NATRIURETIC PEPTIDE RECEPTOR 3-RELATED; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..232
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5013950112"
FT   DOMAIN          52..206
FT                   /note="Receptor ligand binding region"
FT                   /evidence="ECO:0000259|Pfam:PF01094"
SQ   SEQUENCE   232 AA;  26437 MW;  E8A3C48BE4A8A5CF CRC64;
     MYRWVLGVGT LLLSFLVGPV LGDTFKIGYL VPMSDWEVED ADDANRPVGW EVAGAFSLAI
     DDINADNNSI LRTHNLVWDW IDTECFINNG LEKLAEWWKD GYIAAIGPGC TCTHEARFAS
     SVDFPLIDYY CDEDGLSNKE IFPTFVRVIP PIKNCAHVML ATMQMFDWDE VAVVAKNHTK
     YAPVLELMKD LFELNNVTIL HEHYFQPALI HMALRTLSLL YLGRLTHLRE VR
//