ID A0A2G8KM78_STIJA Unreviewed; 467 AA.
AC A0A2G8KM78;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Putative arylsulfatase A {ECO:0000313|EMBL:PIK49111.1};
GN ORFNames=BSL78_14008 {ECO:0000313|EMBL:PIK49111.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK49111.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK49111.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK49111.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK49111.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK49111.1}.
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DR EMBL; MRZV01000480; PIK49111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8KM78; -.
DR STRING; 307972.A0A2G8KM78; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693:SF11; ARYLSULFATASE A; 1.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR Pfam; PF14707; Sulfatase_C; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..467
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013748553"
FT DOMAIN 30..320
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 467 AA; 52685 MW; 47251DB107B344A8 CRC64;
MKDLERYRAV FSSLVFLFSF ATSVTQGSQP NIVILFADDF GYGDLPSYGH PTSEAPSLEK
LIENGLRFTD FYSANPVCTP SRAALLTGRQ PPRTGMYPGV LYPQSSGGMP LEEVTIAEIL
KPLNYRTAIV GKWHLGVGKN NTFMPTNQGF DYYYGIPYTH DMCPCVTCFY PNDTCYYNCN
TKVVSCPLFE NEKIVQQPTD FVTLADDLVI KAKTFIADSV TKKQPFFLYY AFHHTHNPQF
AGKKFRNSTV RGSFGDSLAE MDWNIGEVMS QLKESGVEEN TFVFFTSDNG PCLIFPFRQG
SSGLLKCGKG TTYEGGQRVP ETFFYYPSFS LPYIGVFAVR YKQYKAHYLT AGNSNSGNKN
HDEDCRASAE MTPHAPPLLF DLYQDPSEQF NLNNNADYQE VMTKIYDLKV KYEANMVWRE
SEVEKGFDSS LEPCCNPGCE PFPACCQCSS TYSETEYLKF IPSIDRI
//
