ID   A0A2G8KQ75_STIJA        Unreviewed;       430 AA.
AC   A0A2G8KQ75;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN   ORFNames=BSL78_12961 {ECO:0000313|EMBL:PIK50163.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK50163.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK50163.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK50163.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK50163.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK50163.1}.
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DR   EMBL; MRZV01000431; PIK50163.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8KQ75; -.
DR   STRING; 307972.A0A2G8KQ75; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   PANTHER; PTHR24416:SF600; PDGF-AND VEGF-RECEPTOR RELATED, ISOFORM J; 1.
DR   PANTHER; PTHR24416; TYROSINE-PROTEIN KINASE RECEPTOR; 1.
DR   Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR   PRINTS; PR00109; TYRKINASE.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        38..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          117..394
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   430 AA;  48304 MW;  241C4515BA2D851B CRC64;
     MKVDTMCNDE SCCLYCIEVK ENIEQPSDEQ PTTRQLSIWS SLVIAISSAC FLLAITLSCT
     VICVRGLPTI LTIKSSDSAD IVSDVGIGSD IQMSSMLDET TTEVIPDDLT NIRRDDVSLQ
     TKLAGNGLME YWLATCPSPG VVGGTTIIAK CVSDTAEVKD LLNFRKAANQ LLVLRKHDNI
     VSIIGIAVDD IPFYVYLEYM ENGTLRNFML RNYRQKRDSE SISDSQQRVS SEEQKLNLVR
     FSVDVVEGMS YLFRNKFRHP ALTTSKVLIS VSTGKCKLYD FVPEDHAKDR LLRIIAKKNA
     PLAWLPPESI FFRQYCEKSD VWSLSVALWE IFSLGETPYS GLSGDEIESH IRDGSYLSQP
     MSCPGTIFGV MLSSWDITTS SRPSFEQLQQ RMRLVLASME EDTVNNRMDD NGDNSYFNLE
     EPSCNFNSYI
//