ID A0A2G8KR76_STIJA Unreviewed; 226 AA.
AC A0A2G8KR76;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 22-FEB-2023, entry version 12.
DE RecName: Full=IRS-type PTB domain-containing protein {ECO:0000259|PROSITE:PS51064};
GN ORFNames=BSL78_12636 {ECO:0000313|EMBL:PIK50506.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK50506.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK50506.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK50506.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK50506.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK50506.1}.
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DR EMBL; MRZV01000418; PIK50506.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8KR76; -.
DR STRING; 307972.A0A2G8KR76; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR PANTHER; PTHR21258:SF55; FI23523P1; 1.
DR Pfam; PF02174; IRS; 1.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51064; IRS_PTB; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT DOMAIN 15..117
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 111..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 25216 MW; 8F4A190DD6C271D0 CRC64;
MGNQIQCSPL PGRVKSKLAT NMFKVKNINE QGEIIWRGLI EVNRTELVLH QKNGNPIRWP
LKSLRRYGFD TGLFSFESGR SCATGPATAA ESHTADTSAS QPFNVHDAFN LHQRKNRRRN
TSSSTSVAPT SPVSPTSRAN ASTPIMERSE SPTIEYINSA DIRRLVLHAP RYPPIHRLDL
WGAVTNGTTT KDPTKKVSLN YVHLKLGQDE DDAVLKTEAF KLRPRT
//
