ID A0A2G8KWF9_STIJA Unreviewed; 746 AA.
AC A0A2G8KWF9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13679};
GN ORFNames=BSL78_10787 {ECO:0000313|EMBL:PIK52331.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK52331.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK52331.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK52331.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK52331.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK52331.1}.
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DR EMBL; MRZV01000334; PIK52331.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8KWF9; -.
DR STRING; 307972.A0A2G8KWF9; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12496:SF2; METHYLTRANSFERASE-LIKE PROTEIN 25B; 1.
DR Pfam; PF13679; Methyltransf_32; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT DOMAIN 223..297
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13679"
FT DOMAIN 476..574
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13679"
FT REGION 340..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..359
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 746 AA; 84441 MW; F3E8BDD2891B38DF CRC64;
MVAIRCSRQD KEKIQNYAQS LMLLVSKFRW LTDAYVVEFF VKDHWHALPS SWQEVLDGLK
PHQVGSYLSG NKEVRWGSYL RQQRRAVREV LDDLNPRWVV TSSSKEVRVR KRYLIILIHV
RWVVTSQAAK NCGKKEVGSY LRQQRSAVRK RYLMSQSTLS GSYLSGSKEV RHTTVWPLSL
LAFCAATQSL TLNRFPGVAE YPNPVEKLPD QLDHCFKFHV KIKKRHEIQT LADIIHNTCK
LSKVRRVVDV GGGLGHLTRL LSVGYGLKVM SIEAAGCHVN GAAKVDRKVE VLMEKRKKKG
ILDLPKLSAS PLQRPVHIVC NINPDISVKE FVKIVNQHMS EEQDSEGLDQ VEDKSEGSCT
GDSFEGYESS EKDKSEGVKM NEVMKVTGDG SLSANKPVPP QSRLSPDNSK ETHCREMTDK
TSLHSSTEPI LKLFSSNDQT AQVTNRNRKI SARSQEVPAE NERIVKVDQN REDDTNLTYS
QRFLPDAESP DQSVFLSNDS TLCESEHLGR PDLADTDVNV LSQIKSTNSE GNAVFTLIGL
HTCGDLGPTI LRLFIRCREA KVLALVGCCY MKMQYVQPIK ELDMMNFHEA GFPMSDWVKS
LCGSPLTFEP LELACHFFDN YYQRLKEKEP DLVKTHAGFI QIKKATGSIK KLHGMSFQCY
ANAVFRKLGL TFDPLAAHQL EELHRPHWGR LIIFHSLRLC LAPIVESLIL IDRMLYLLEN
GVESQLTAVF DPFISPRNFL LQATKA
//
