ID A0A2G8L1R6_STIJA Unreviewed; 347 AA.
AC A0A2G8L1R6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Putative WSC domain-containing protein 2 {ECO:0000313|EMBL:PIK54208.1};
GN ORFNames=BSL78_08888 {ECO:0000313|EMBL:PIK54208.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK54208.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK54208.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK54208.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK54208.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- SIMILARITY: Belongs to the WSCD family.
CC {ECO:0000256|ARBA:ARBA00010236}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK54208.1}.
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DR EMBL; MRZV01000258; PIK54208.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8L1R6; -.
DR STRING; 307972.A0A2G8L1R6; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR45964:SF5; WSC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45964; WSCD FAMILY MEMBER CG9164; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 117..289
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 347 AA; 40558 MW; 7FB4167DFEA668BE CRC64;
MDMKSATQKI TKYSWTGLFL ILFMLYIVRN THPDLSDRQS RPIKFQRDTV VYDVSPKEKK
RKGSTNSGVT MQRRGNLLYP MVNVTNFPRI DDLDEEECQA MMDDVIVAPA SSMPLIALAS
FPRSGNTWTR SLLQVATGYS TGSVHWESER NRQRVQEWFL AGTEDYMRQT GVCVKTHEFS
IDHIPIFNNG AIILIRNPYY SVVSDYFRFF GGLKNISRDQ LVESMESRND HWTKVLLPQF
QRWKLTNINW INNCKRLLVV FFEDLERDPV RELTRMVTFL GQPLLPRRIM CAIYNFRPME
AHRSHMNFDP YTPEMHAILD SYIQEVNITL LQKGGNPLPT YEKYALT
//
