ID   A0A2G8L3F5_STIJA        Unreviewed;       634 AA.
AC   A0A2G8L3F5;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Transcription initiation factor TFIID subunit 6 {ECO:0000256|ARBA:ARBA00040091};
GN   ORFNames=BSL78_08294 {ECO:0000313|EMBL:PIK54772.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK54772.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK54772.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK54772.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK54772.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF6 family.
CC       {ECO:0000256|ARBA:ARBA00007688}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK54772.1}.
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DR   EMBL; MRZV01000234; PIK54772.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8L3F5; -.
DR   STRING; 307972.A0A2G8L3F5; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR   GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR   CDD; cd08050; TAF6C; 1.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR037796; TAF6.
DR   InterPro; IPR011442; TAF6_C.
DR   InterPro; IPR046344; TAF6_C_sf.
DR   InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR   PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR   PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR   Pfam; PF02969; TAF; 1.
DR   Pfam; PF07571; TAF6_C; 1.
DR   SMART; SM00803; TAF; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          11..75
FT                   /note="TATA box binding protein associated factor (TAF)
FT                   histone-like fold"
FT                   /evidence="ECO:0000259|SMART:SM00803"
FT   REGION          467..634
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        521..600
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   634 AA;  68897 MW;  86D83D5AB0391799 CRC64;
     MADPQKERKA SVLSHESMKV IGETVGLPTL PDEASYALAE DATFRLKMLV QEAVKFMRKA
     KRRKLSTSDF DSSLQDQNIE PLYGLTVPDK IPFRFTSGGG RELHFVEEKE FDLSEMISSP
     LPKVPLDVSL KAHWLCVEGV QPAIPENPPP VDQEKQKVES TKATTHQKPV INNKNDKEGE
     KDRVLTLLNK AKDVTKEMRK AKDILSHELS VEQQLYYKEI TEACVGSSEP KRAQALQSLA
     SDSGLYQMLP RFSSFICEGV RVNVVQSNLA LLIYLMRMVK ALMDNPTLYL EKYLHEIIPA
     VVTCIVSKQL CLRPDIDNHW ALRDFAARLM ASICKKFSTS TNNIQARVSK TFDKSLSVDL
     APLPTLYGAF AGLSELGPEV IKVIVMPKLK PLSERIKSVR DSSLSSNFDK IAAEHLKSLV
     LKQCSPYLKQ VRTGPDTPDA YIEDFGPIGS ALCNQVQKLR AQPGLAVNKP TIQIPPPRQS
     PLGSGPRTPT SGLSMSRSPG FPLMGDIKGP IPRSISVPGG PLTPTGKQSK FSPMSSSMAQ
     KSKSSGSSVL IGGISSKPGS GKGGSSSSLS PSGLSKSAAF TFTGSMRDES GLSQSMSSAE
     GRRRSGEEGG NNGASMLMSL AHAATMQAPY KTKE
//