ID A0A2G8L5U0_STIJA Unreviewed; 561 AA.
AC A0A2G8L5U0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Elongation factor 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BSL78_07581 {ECO:0000313|EMBL:PIK55500.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK55500.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK55500.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK55500.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK55500.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK55500.1}.
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DR EMBL; MRZV01000213; PIK55500.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8L5U0; -.
DR STRING; 307972.A0A2G8L5U0; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR CDD; cd03700; EF2_snRNP_like_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT DOMAIN 323..440
FT /note="Translation elongation factor EFG/EF2"
FT /evidence="ECO:0000259|SMART:SM00889"
FT DOMAIN 442..531
FT /note="Elongation factor EFG"
FT /evidence="ECO:0000259|SMART:SM00838"
SQ SEQUENCE 561 AA; 62693 MW; C550909400A23895 CRC64;
MFDAIMNFKK EETSKLLDKL DLTKKLDAEE KDMEGKPLLK RVMRKWLPAG EALLQMITIH
LPSPVTAQKY RMEMLYEGPH DDAVAIGIKE CDPNAPLCMY ISKMVPTTDK GRFYAFGRVF
SGKVATGQKC RIMGPNYVPG KKDDLNCKQI QRTILMMGRY IEAIEDVPCG NICGLVGVDQ
YLVKTGTITT FEQAHNLRVM KFSVSPVVRV AVEAKNPGDL PKLVEGLKRL SKSDPMVQIL
TEESGEHIVA GAGELHLEIC LKDLEEDHAC IPIIKSDPVV SYRESVTGAS NQTCLSKSPN
KHNRLFFTAV NMPEDLAKDI DEGEVKPRQD IKTRARYLAE KYDYEVTEAR KIWAFGPEGT
GPNLLMDVSK GVQYLNEIKD SVIAGYQWAT KEGVLCDENM RGVRFNIHDV TLHADAIHRG
GGQIIPTARR VLYASVLTAE PCILEPVYLV EIQCPEDAVG GIYGVLNRRR GHVFEDSQMP
GTPMFIVKAY LPVNESFGFT ADLRSKTGGQ AFPQCVFDHW QVLPGNVFDK ASKPGEVVHN
TRKRKGLSEE VPPLEKYLDK M
//
