ID   A0A2G8L664_STIJA        Unreviewed;       595 AA.
AC   A0A2G8L664;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Transposon Ty3-G gap-Pol polyprotein {ECO:0000313|EMBL:PIK55728.1};
GN   ORFNames=BSL78_07388 {ECO:0000313|EMBL:PIK55728.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK55728.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK55728.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK55728.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK55728.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK55728.1}.
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DR   EMBL; MRZV01000203; PIK55728.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8L664; -.
DR   STRING; 307972.A0A2G8L664; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR001969; Aspartic_peptidase_AS.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33327; ENDONUCLEASE; 1.
DR   PANTHER; PTHR33327:SF3; RNA-DIRECTED DNA POLYMERASE; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS00141; ASP_PROTEASE; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT   DOMAIN          411..588
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   595 AA;  67261 MW;  0900FAE5FDBFC36F CRC64;
     MTDPEKKTET QSRLAAVSLK LPPFWPNDPT IWFAQVEAQF TTRGITSEQT QYAYVVASLQ
     PEIAQEVRDL LLHTPAKQPY STLKSELIKR TSASEQRRLH QLLISEELGD RKPSQLLRRM
     RQLLGDSKLE DNFLRQLFLQ RLPTNVQLIL ATTSETIDVE QLAVIADKIM EVTPSVHQVS
     AIAPTPTVNS VNAPSTEIAE LREMVAALTL KVEALGRQQG NRTNRSRSKP RDGSRFLVDT
     GAEVSVFPAT KVEKGKQPLF TLNAANQTPI SAFGERSFTL DIGLRRVYRW VFILADVASP
     LLGADFLAHF SLAVDVKHRK LIDLETSLSV NVRTSTDTSP SPSYRISNLQ SQYHALLDTY
     PDITRPCYKE TAIKHNITHH IITKGTPVFA RPRRLVSDKY RIAKDEFEHM IQLGIVRPSE
     SCWSSPLHMV PKKSGDWRPC GDYRALNNST VPDRYPIPHI HDFTSSLHGK TIFSKIDLVR
     AYHQIPVEPD DVPKTAITTP FGMFEFVRMP FGLRNSAQTF QRFIDQVLRG LPFVYAYIDD
     LLIASSSHEE HYDHLRQLFD RLHEHGIVIN PSKSIFGVSS LDFLGHHVDA SGILH
//