ID   A0A2G8LA92_STIJA        Unreviewed;      1274 AA.
AC   A0A2G8LA92;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Putative neurobeachin {ECO:0000313|EMBL:PIK57179.1};
GN   ORFNames=BSL78_05931 {ECO:0000313|EMBL:PIK57179.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK57179.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK57179.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK57179.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK57179.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK57179.1}.
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DR   EMBL; MRZV01000151; PIK57179.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8LA92; -.
DR   STRING; 307972.A0A2G8LA92; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   Gene3D; 2.60.120.200; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR   InterPro; IPR046852; Neurobeachin_a-sol.
DR   PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR   PANTHER; PTHR13743:SF160; NEUROBEACHIN; 1.
DR   Pfam; PF15787; DUF4704; 1.
DR   Pfam; PF13385; Laminin_G_3; 1.
DR   Pfam; PF20425; Neurobeachin; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT   DOMAIN          7..118
FT                   /note="Neurobeachin alpha-solenoid region"
FT                   /evidence="ECO:0000259|Pfam:PF20425"
FT   DOMAIN          375..864
FT                   /note="DUF4704"
FT                   /evidence="ECO:0000259|Pfam:PF15787"
FT   REGION          908..955
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          985..1028
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1188..1212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        925..955
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1274 AA;  143852 MW;  34FA72A53DFA7EDA CRC64;
     MCSGGRLLVG GEFDLESNFT IQDAENILHM LELMDHCSPT LQAEIWSMCA AILRKSLLNL
     QACTEISLIE KLVSRMKISD EMLADLLVEV IGVLASYSIS VRELKLVFSY LKATNDKWPR
     YSIKLLKALR MIPKKHGPDV FFSFPGKNGS TIALPPIKTW PYQNGFTFST WFRVEPLSNI
     ERDKPYLYCF RTGKGVGYSG HFMGSCLVVT SVKVKGKGFQ HCVKFDFQPH KWYMVSIVHV
     YNRWRTSEIK CYVDGQLVSS GEMQWNINTS DPFDKCFLGS APSADKERTF AGQMASVYLF
     SEALTPQQIT GIFRLGPNYK NHFKFPSESD ISLPDTYKKV LYDGKLTQSI VFLYNPAATE
     SQLCLDSSPK GNFSYFVHSP HALMVQDVRS IVTHSIHSTL HSIGGIHMVF PFFTQLDFPQ
     ASPDDAKEGA DARSRTEFEI GTLLLGFLCD LLKQSMSTQQ QMVHGRGFIM LGYLLQKAGT
     NHITESALET FLDLAKHFNN LPSGVQLLRH LVDHILFNPA LWIHTPTKVQ ISLYTFLANE
     FVGQASIYTN IRRVSTVLQL MHTLKYYYWI DNPESRSGIA PRGLEGDRPK SQDLIHLRGL
     ILSITKQLIL KEKTSNDEEL QIILNYLVTI HEDANLRDVL QLLMSLMAEN LNGLAVAFDR
     KNGTRVIFKL LASGDEMVCA MALKVLALFL SRLPSKRKMD LMYGQNLYSL IGERIQLNCN
     TLSMTMYNCL FEVLSERVTM AVMSSKHPDQ DRTYRILNPG MFHVMARLIR QSAPSAEAME
     VRKLFLSDMI LLFNNSRENR RILLQCSVWQ DWMLGLAYIY PKTDEEKRVT EMVYSVLKML
     LHHAMKYEWG GWRVWVDTLS IIHSKVSFED HKNEMLRAYN NYQQQQANGQ SAPLTVAGAV
     SGSVQGAPAL APRTSPSALC SDDRGDVEYT VRERNKERTD GDDIPERDQA RGVSSEREKE
     VLTLLEDVMD DVVKIVEGRG KTPENVKRMT EEAETKKQKA MSGPSQVAAA GPDKPVDPRG
     QVFSPGPHQA PYRIPEFSWS HMHQRMMSDL LFAIETDIQV WRSQSSKTVI DFVNAVENNI
     FVQNVTQMVS QIMDNLIYSC GGILPLLSSA TSRHEPDITE PTQNLPLEVG ISFINRIMNL
     VDVLVFASNQ NFADLESEKN MTKGGILRQC LRLTCFCAIR NVLECRYRTN PSPTPSRQSF
     SAGDNKEPVS PTGSIQTLIE ATQPSTKLSN RFHVNIFNVH MLLLDVPVRS VSPPPTGSIQ
     TLIEATQPFT TVSN
//