ID   A0A2G8LEA9_STIJA        Unreviewed;       620 AA.
AC   A0A2G8LEA9;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN   ORFNames=BSL78_04451 {ECO:0000313|EMBL:PIK58608.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK58608.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK58608.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK58608.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK58608.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK58608.1}.
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DR   EMBL; MRZV01000107; PIK58608.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8LEA9; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   Pfam; PF08205; C2-set_2; 1.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; Immunoglobulin; 3.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..620
FT                   /note="Ig-like domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5013688116"
FT   TRANSMEM        574..593
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          397..496
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   620 AA;  68539 MW;  51E678F8F95B3690 CRC64;
     MKNATITAVL FLLAIHQGSA NFQCPSATFV ELGKDVRIDC LISDVNDIYW LRGTEEDHYP
     IVKIEMGLKT ISKVAQDHFD ITDTGALVIR DALNDLTGSY VMLHYRTDLV REVDTVTLNV
     TTLVDSIIIQ GPSGGVYPMG SNITLTCTFQ KGYVVGWKEY ENKDIFVADT KVTADTKYDN
     FCVSLSDRVS NLQIIGAELE DAGKYSCNTE SYAHVEIEAP PSFRIIFNDT NDGGTDSTDS
     HGVIDITCIA RNARPAVMIR FETDGSEWIN PSETWTVSNG VTFDTYATLK YNFRKNQTDV
     FLTCQTFGQK TVPPIEKIIH LFTPTCSLEM SNTEATCICI SNPPVYKYMI SIDGKLEVGK
     SLNVENFDGS NISCIGVNYI GVGISMFRVV ESINAQPSLR IMFNFTDDEG NNSTESHGVI
     DITCIARNAR PAVMIRFETD GREWINPSET RTVSNGVTFD TSATLKYSFV KNQTDVFFTC
     QTFGQGTVPP MEKTLHLFTP TCDLHVNTIE ASCNCTSNPP VYKYILSIDG KMEVGKTLNV
     ENLVGSTIIC TGVNYIGVGT SKAIIVESNT GSSYLVYVIC SVVVILGAVI VVFRRRKKSN
     LCYRNYCDLV ITTVLHIPSE
//