ID   A0A2G8LG18_STIJA        Unreviewed;       912 AA.
AC   A0A2G8LG18;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Putative tudor domain-containing protein 5 {ECO:0000313|EMBL:PIK59187.1};
GN   ORFNames=BSL78_03884 {ECO:0000313|EMBL:PIK59187.1};
OS   Stichopus japonicus (Sea cucumber).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC   Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX   NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK59187.1, ECO:0000313|Proteomes:UP000230750};
RN   [1] {ECO:0000313|EMBL:PIK59187.1, ECO:0000313|Proteomes:UP000230750}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Shaxun {ECO:0000313|EMBL:PIK59187.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:PIK59187.1};
RX   PubMed=29023486;
RA   Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA   Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA   Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA   Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT   "The sea cucumber genome provides insights into morphological evolution and
RT   visceral regeneration.";
RL   PLoS Biol. 15:E2003790-E2003790(2017).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIK59187.1}.
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DR   EMBL; MRZV01000090; PIK59187.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G8LG18; -.
DR   STRING; 307972.A0A2G8LG18; -.
DR   Proteomes; UP000230750; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR   CDD; cd08824; LOTUS; 2.
DR   CDD; cd09972; LOTUS_TDRD_OSKAR; 1.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 2.40.50.90; -; 1.
DR   Gene3D; 3.30.420.610; LOTUS domain-like; 4.
DR   InterPro; IPR041966; LOTUS-like.
DR   InterPro; IPR025605; OST-HTH/LOTUS_dom.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR002999; Tudor.
DR   PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22948:SF80; TUDOR DOMAIN-CONTAINING PROTEIN 5; 1.
DR   Pfam; PF12872; OST-HTH; 4.
DR   Pfam; PF00567; TUDOR; 1.
DR   SMART; SM00333; TUDOR; 1.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR   PROSITE; PS51644; HTH_OST; 4.
DR   PROSITE; PS50304; TUDOR; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230750}.
FT   DOMAIN          7..80
FT                   /note="HTH OST-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51644"
FT   DOMAIN          144..216
FT                   /note="HTH OST-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51644"
FT   DOMAIN          355..428
FT                   /note="HTH OST-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51644"
FT   DOMAIN          451..524
FT                   /note="HTH OST-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51644"
FT   DOMAIN          616..675
FT                   /note="Tudor"
FT                   /evidence="ECO:0000259|PROSITE:PS50304"
FT   REGION          88..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          229..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..109
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..132
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        251..272
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   912 AA;  104174 MW;  FF06C57B5CCC30F6 CRC64;
     MTDKAKLRDS VKKNVRALLI SAPMGLSMRE MERDYAEVIC EPIPALQLGF NSAQDLLLDM
     PDVARPQWER GNLVLFGVAD NTTKHIQRMV SRQRKDKAKI QKKRAAVNRS SRYTRNTQQP
     PRKKLPSSSF SSRSFRAPAV TASVPASLQS QVKNILKKHP AGISNDEFEL TFYQYQNYNI
     NFKKLGFQTL WEFFRAIPGV KASHTSKDEY DIFLVPGIVH AIPAGYEDRR RDDVEETGSS
     LSSDYMHKGQ VRPNNQHERK SSSERQRDYP RENLPPRLSG QRMAPTNSRS PWALAGVPQP
     MKKAPITRGR GKSSDELPIE SPNQKRSWTA VPVVKEDDND DDAFLPIEQD VEAPFEKDFV
     EDIKRILAKH SNGLWSIELP DEYKKLTGKP LKIFAMGYFS VVELVSAMPD VVTVVREDTS
     DWKLYDARKK KNEPRLEPSF QDDDFNSEDN TLEEVKASLR ELLEDIKDGI LLEDLQSAYE
     RKYSRILPLQ RLGFHDIDSL VLLIPDVVKV VYKGHGKVYA FAERETQGIP KYDSKMAILC
     SLPQDAVGFG YKYRDSEMPL LDQYFEVYVS SVCTPHKMTI QLRDKEQNTA LEELMDDLEA
     IYKYPEGERY FFPTSMIAVN QLCCALYLED NNWHRAIITG VIDNDFVEVN YIDYGSTLQV
     PKSCLRLLKA CFLKLPAAAL DAKLANVEPL EDKWSSASRD RLLELTSEKP LIAYCTEIKN
     KVLSLFLCDT TTESDIHIND LLVQEDIFYR VVEPNDKTMF NDPSQGSEGT FQNISGFDPS
     DFVTTVEQIP GLDQVSEGSQ DEYPNEIYPT DGDASGIAFH QERKKRLNKV LLQKISLEDM
     EEIEENNLNL EDILLTMKFL EGRRKRLLAV LSSDEGVNAV DDLDETETLI RHFEERKTKI
     SQRKPKGLYV AT
//