ID A0A2G8LHC5_STIJA Unreviewed; 496 AA.
AC A0A2G8LHC5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Sushi domain-containing protein 2-like {ECO:0008006|Google:ProtNLM};
GN ORFNames=BSL78_03389 {ECO:0000313|EMBL:PIK59658.1};
OS Stichopus japonicus (Sea cucumber).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Holothuroidea;
OC Aspidochirotacea; Aspidochirotida; Stichopodidae; Apostichopus.
OX NCBI_TaxID=307972 {ECO:0000313|EMBL:PIK59658.1, ECO:0000313|Proteomes:UP000230750};
RN [1] {ECO:0000313|EMBL:PIK59658.1, ECO:0000313|Proteomes:UP000230750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Shaxun {ECO:0000313|EMBL:PIK59658.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:PIK59658.1};
RX PubMed=29023486;
RA Zhang X., Sun L., Yuan J., Sun Y., Gao Y., Zhang L., Li S., Dai H.,
RA Hamel J.F., Liu C., Yu Y., Liu S., Lin W., Guo K., Jin S., Xu P.,
RA Storey K.B., Huan P., Zhang T., Zhou Y., Zhang J., Lin C., Li X., Xing L.,
RA Huo D., Sun M., Wang L., Mercier A., Li F., Yang H., Xiang J.;
RT "The sea cucumber genome provides insights into morphological evolution and
RT visceral regeneration.";
RL PLoS Biol. 15:E2003790-E2003790(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIK59658.1}.
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DR EMBL; MRZV01000076; PIK59658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8LHC5; -.
DR Proteomes; UP000230750; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR13802; MUCIN 4-RELATED; 1.
DR PANTHER; PTHR13802:SF59; NIDOGEN; 1.
DR Pfam; PF00084; Sushi; 1.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM00032; CCP; 1.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR PROSITE; PS50923; SUSHI; 1.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230750};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 441..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..296
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 373..430
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 474..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 401..428
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 496 AA; 55159 MW; 4B8246925C1675B7 CRC64;
MEALNLTKIH LLNIITRELR RVIDQDQEEV DNSAVMDPMV IYSLDLPEAG RLMPMLLWLG
GTLKHFWFDV LPFIACCKLT SQCETYYEFR PSDDCSDYQP PRPTIGTGDP HFISLDGKEF
TFNGAGEFVL VKSSLHNFTF QTRMEVLAGT DASVYTSFVL SSDISDTIQV QRSPLNGTLI
LLNGEPIDLY FDGYLIRKQD FRGLRLTVNP DVSEITVRLH IGATALIRIT SEMMSFILQL
PDALKGQTEG LLGNFNDNAD DDFILRNGSS LLHNSTLEEI HFDFGLGWIL DTNTSKFTYL
PPYDFSTFFH PDFIPNLVYP DVNSVSEEVK LICGESITCL YDAVTTNSTT FANDSLQDIK
TYETVNENLV KIVSCGQPGK IENGAINGSV FLVGYTVVAS CNEGFYLDGN SELLCYSNGT
WSGNLPICIE IPIANNTPPT VIIVITSVIG SLVLIAIIVV IIKKFCLYSS KISSGHGPTN
ENIPSENKAF EHDEYQ
//
