ID A0A2G8RWL5_9APHY Unreviewed; 881 AA.
AC A0A2G8RWL5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=VHS domain-containing protein {ECO:0000259|PROSITE:PS50179};
GN ORFNames=GSI_11662 {ECO:0000313|EMBL:PIL25909.1};
OS Ganoderma sinense ZZ0214-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Ganoderma.
OX NCBI_TaxID=1077348 {ECO:0000313|EMBL:PIL25909.1, ECO:0000313|Proteomes:UP000230002};
RN [1] {ECO:0000313|EMBL:PIL25909.1, ECO:0000313|Proteomes:UP000230002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZZ0214-1 {ECO:0000313|EMBL:PIL25909.1,
RC ECO:0000313|Proteomes:UP000230002};
RX PubMed=26046933; DOI=10.1038/srep11087;
RA Zhu Y., Xu J., Sun C., Zhou S., Xu H., Nelson D.R., Qian J., Song J.,
RA Luo H., Xiang L., Li Y., Xu Z., Ji A., Wang L., Lu S., Hayward A., Sun W.,
RA Li X., Schwartz D.C., Wang Y., Chen S.;
RT "Chromosome-level genome map provides insights into diverse defense
RT mechanisms in the medicinal fungus Ganoderma sinense.";
RL Sci. Rep. 5:11087-11087(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIL25909.1}.
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DR EMBL; AYKW01000045; PIL25909.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8RWL5; -.
DR STRING; 1077348.A0A2G8RWL5; -.
DR OrthoDB; 1383625at2759; -.
DR Proteomes; UP000230002; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd21383; GAT_GGA_Tom1-like; 1.
DR CDD; cd16980; VHS_Lsb5; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR045007; LSB5.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47789; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR PANTHER; PTHR47789:SF2; VHS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230002}.
FT DOMAIN 247..369
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 136..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..416
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..571
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..779
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..819
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..847
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 881 AA; 98523 MW; 6E795BBAF69FA2AF CRC64;
MKKLFGRDKP KPVKVTPGGR DDGSALGEPH AYAPRRNGDI HPGPEDQWDL ISETDPPLQP
LRPPNLGLSQ TSSFGSINHS NVPVSAPLPR STSPFSVNTS MPPPSMKSSK ERDGAVLRKK
PPAPVNAFAA VGILNSLNPT HHLEPVNSRE TSEDGYTDAS WKEEKEKKEK RPFWDRSGHK
EKEKEKEKER AREREKERER DRERERERER EHEREVMRER ERESTRREEG TPMEITRMLG
FLFATSSEDW TLVLDVCDKA SANEENAKEA AKALRKEFKS GEPSTQLAAA RLWAIMLRNC
SILFVKHCAS RKFIETLDEV LKAKTTPPVV RERLLQVLAA ASYASDHESN FRHLWRKYKR
EDQPDEGVPF DTDDAMFYPA TPRHSIGPNS LTPPVLEQPF QPQPLQPQPL HPQSLTPGQP
PVQHRSSSQP QYPQQPPHSQ SPLQRPPLTT TPGRVKSHSS RHRVIPPEED IRRLFQECKV
GKGNASLLSE ALTYAKPEDL KSKDIIKEFY ARCRASQELI SAQIPWAFAQ AERSREAAGI
PLDPTRDTRV SVDRDRDRPP LSPKKEKDEH LTTEEKLLAA ILASNEDLLE ALRQYDDLER
VGIERDAEER SKREIRMDRS RLVYDDNNEA HYLEPGNANP GGASSSRSPS PSPSPSPSPA
PSLVVTPSNM QNNISQPIPT RPQPSSNHTH TDRNPQHTQH AGSQGSVQSL APPPPAPHGP
RLPIQRSNTP SPERRSLSRG PGPDPGPDSG PGRTSIDSTQ GSAVAVPTPS RLRQNSSSEW
SELGDDEECK TPVRPSAKAL GKRKVIEPAE GDRPFDPDDL FYDQSVNESI RTSDDSDSDD
GHAKNPWHRP VHYVYDAAAE RTEQRIREGR LAAAAVVAGV H
//
