ID A0A2G8SMY9_9APHY Unreviewed; 553 AA.
AC A0A2G8SMY9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=GSI_02923 {ECO:0000313|EMBL:PIL35134.1};
OS Ganoderma sinense ZZ0214-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Ganoderma.
OX NCBI_TaxID=1077348 {ECO:0000313|EMBL:PIL35134.1, ECO:0000313|Proteomes:UP000230002};
RN [1] {ECO:0000313|EMBL:PIL35134.1, ECO:0000313|Proteomes:UP000230002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZZ0214-1 {ECO:0000313|EMBL:PIL35134.1,
RC ECO:0000313|Proteomes:UP000230002};
RX PubMed=26046933; DOI=10.1038/srep11087;
RA Zhu Y., Xu J., Sun C., Zhou S., Xu H., Nelson D.R., Qian J., Song J.,
RA Luo H., Xiang L., Li Y., Xu Z., Ji A., Wang L., Lu S., Hayward A., Sun W.,
RA Li X., Schwartz D.C., Wang Y., Chen S.;
RT "Chromosome-level genome map provides insights into diverse defense
RT mechanisms in the medicinal fungus Ganoderma sinense.";
RL Sci. Rep. 5:11087-11087(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-
CC O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+);
CC Xref=Rhea:RHEA:67452, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30879, ChEBI:CHEBI:171667, ChEBI:CHEBI:171668;
CC EC=3.1.1.117; Evidence={ECO:0000256|ARBA:ARBA00024511};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:67453;
CC Evidence={ECO:0000256|ARBA:ARBA00024511};
CC -!- SIMILARITY: Belongs to the carbohydrate esterase 15 (CE15) family.
CC {ECO:0000256|ARBA:ARBA00010092}.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIL35134.1}.
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DR EMBL; AYKW01000004; PIL35134.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8SMY9; -.
DR STRING; 1077348.A0A2G8SMY9; -.
DR OrthoDB; 1446144at2759; -.
DR Proteomes; UP000230002; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF162; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000230002};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 20..553
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5013431993"
FT DOMAIN 29..517
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 553 AA; 59222 MW; C3AC3334D594CECE CRC64;
MLVRSSLSLL ALFAGAALGL PVEVEKRASP TVLLDQGTFV GSSDGTTNKF LGIPFGKAPV
GNLRFSLPVA VDAYNGTQTV TSYGPACPQQ AFDFPQIPGL VGDVADWFVN TIYNVITPSA
EDCLSLNVIV PAGTKAGANL PVAVWIFGGG FEIGGPDIYD GSVIVKRSIE LGEPVVYVSM
NYRVSAYGFL ASQEVKDAGV GNLGLQDQRL ALRWVQKYIS TFGGDPSKVT IWGESAGAIS
VALQMLTNGG NTEGLFRGAF MQSGSPIPVG DITHGQNDYD TLVSATGCSG AADTLQCLRE
VPFATLKQAV DSSPGIFSPQ SLRLAWLPRV DGKFLVDAPQ KLVQQGSVAN IPFVNGDCDD
EGTLFSLSNI NVTTEDEVRS YLSSNYISGI SSSDLDQLLT LYPSDITQGS PFDTGILNVV
TPEFKRLASI QGDLVFQAPR RFFLQNTADK QPVWSYINKR LKVTPILGSA HGTDILNVYG
GSDMADHVIN FVNNLDPNGA TVISWPKYTT ASPQLLEYYD TIIPGINGLQ LTTDDYRVDA
MNFMTQLSLE FPI
//
