ID A0A2G8T5X5_9BURK Unreviewed; 549 AA.
AC A0A2G8T5X5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC domain-containing protein {ECO:0000259|Pfam:PF02570};
GN ORFNames=CR103_02325 {ECO:0000313|EMBL:PIL41363.1};
OS Massilia psychrophila.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Massilia.
OX NCBI_TaxID=1603353 {ECO:0000313|EMBL:PIL41363.1, ECO:0000313|Proteomes:UP000228593};
RN [1] {ECO:0000313|EMBL:PIL41363.1, ECO:0000313|Proteomes:UP000228593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 30813 {ECO:0000313|EMBL:PIL41363.1,
RC ECO:0000313|Proteomes:UP000228593};
RA Wang H.;
RT "Massilia psychrophilum sp. nov., a novel purple-pigmented bacterium
RT isolated from Tianshan glacier, Xinjiang Municipality, China.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIL41363.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PDOB01000002; PIL41363.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G8T5X5; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000228593; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03414; CbiX_SirB_C; 1.
DR CDD; cd03416; CbiX_SirB_N; 1.
DR Gene3D; 3.40.50.1400; -; 2.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR002762; CbiX-like.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR Pfam; PF01903; CbiX; 2.
DR SUPFAM; SSF53800; Chelatase; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000228593}.
FT DOMAIN 332..526
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 549 AA; 59152 MW; 9BE4CB47D43D0758 CRC64;
MNDIDNIDGT AQVDKFDKLG KLGIVVAGHG SRDPDAVREF EALVELVRLR APLHVVHHGY
LEFSSPTIAE AVAANIAAGA KQVAVVPGVL LAARHAKNDM PSEVQALTLA YPSIDLYFGA
PLSPHPRLLQ LAQERVLEAE ATSPLTVRRS DTCLVLVGRG TTDPDANGDI AKLARMLEEG
MGFGGVHVCY SGTAKPLVAD GLRSAAQLGF ARLVVLPFFL FDGVLIKRIY AAVEELQLRE
PGLEVLKAAY LGAHPHVADV IIERAVEAVE GRAAMNCSLC KYRVQIVGFE NQVGEPQQGH
HMAVRGLLEQ ERSGAVAAVE APVFQPYLPH PIEAESFKII AAGRDWTPFP AAHLTVLQRL
VHTSGDFDVV EDIYFSSGAV ENGIRALLRC KLVVTDVTMV QTGLKRELLK QLGIDTWCGV
HERETFLMAA ALGTTRSAAG IRRAWEKFGN DIVLAIGDAP TAIMEATRLI RDHGWRPQLV
IGLPVGFVGT RESKADLQRC LQVPRITNSG TRGGSPWAAS VVNGLMIDAL NELASNQLAS
NERTSNGET
//
