ID A0A2G9G7Z4_9LAMI Unreviewed; 760 AA.
AC A0A2G9G7Z4;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=CDL12_26082 {ECO:0000313|EMBL:PIN01409.1};
OS Handroanthus impetiginosus.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Bignoniaceae; Crescentiina; Tabebuia alliance;
OC Handroanthus.
OX NCBI_TaxID=429701 {ECO:0000313|EMBL:PIN01409.1, ECO:0000313|Proteomes:UP000231279};
RN [1] {ECO:0000313|Proteomes:UP000231279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UFG-1 {ECO:0000313|Proteomes:UP000231279};
RX PubMed=29253216; DOI=10.1093/gigascience/gix125;
RA Silva-Junior O.B., Grattapaglia D., Novaes E., Collevatti R.G.;
RT "Genome assembly of the Pink Ipe (Handroanthus impetiginosus,
RT Bignoniaceae), a highly valued, ecologically keystone Neotropical timber
RT forest tree.";
RL Gigascience 7:1-16(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIN01409.1}.
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DR EMBL; NKXS01006431; PIN01409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G9G7Z4; -.
DR STRING; 429701.A0A2G9G7Z4; -.
DR OrthoDB; 608at2759; -.
DR Proteomes; UP000231279; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11764:SF19; TERPENE CYCLASE_MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003, ECO:0000313|EMBL:PIN01409.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000231279};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 99..363
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 414..751
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 760 AA; 87310 MW; 4BA0329939AC4280 CRC64;
MWKLKIAEGE GQPWLRSTNG HIGRQHWEFD AEAGTPEERA QVERMREEFK KNRFRIKQSA
DLFMRMQLRK ENPFDPIPAP IQVKETEKIT TEAIITTLRR ALSFFSTIQA HDGHWPAESA
GPLFFLPPLV LALYVTGGIN AVLSPQHQKE IIRYIYNHQN DDGGWGTHIE GHSTMFGSVL
SYITLRLLGK GPEDGEDKAV ARGRKWILDH GGAIGIPSWG KFWLTVLGVY EWDGCNPMPP
EFWLLPNFSL IHPGKMLCYA RLVYMPMSYL YGKRFVGPLT RLVQSLRQEI YTQPYHEINW
NKARNTCAKE DLYYPHPFVQ DMLWGFLYHF TEPVLKRWPF SKLREKALRI AMEHVHYEDK
NSGYICIGGV EKVLCLIACW VEDPNSEACK WHVARIPDYL WVAEDGMKMQ SFGSQMWDVA
FAIQAILSAN LAKKYGPTLR KAHNFVKASQ VRDNRTGDFH KMYRHTSKGS WTFSMRDHGW
QVSDCTAEGL KVALLLSQMP PELVGEKIET ERLYDAVNLI LSLQSANGGF PAWEPKRAQR
WLEKFNPTEI FEDTLIERDY VECTASAMQS LTLFKKLHPN YRRNKIESCI SRAIQYIENT
QQPDGSWYGR WGICYTYGTW FAVEGLVACG KNYHNSSTLR KACEFLLSKQ LVDGGWGESY
LSSANMVYTN LEDNRSNLVQ TSWALLSLIA AGQAEIDSLP IHRGMRLLIN SQMEDGDFPQ
QSITGIFMKS CTLNYSCHRN IFPIWALGEY NARVLEASTK
//
