ID A0A2G9HYM9_9LAMI Unreviewed; 749 AA.
AC A0A2G9HYM9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Tripeptidyl-peptidase II {ECO:0000313|EMBL:PIN22583.1};
DE EC=3.4.14.10 {ECO:0000313|EMBL:PIN22583.1};
GN ORFNames=CDL12_04695 {ECO:0000313|EMBL:PIN22583.1};
OS Handroanthus impetiginosus.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Bignoniaceae; Crescentiina; Tabebuia alliance;
OC Handroanthus.
OX NCBI_TaxID=429701 {ECO:0000313|EMBL:PIN22583.1, ECO:0000313|Proteomes:UP000231279};
RN [1] {ECO:0000313|Proteomes:UP000231279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UFG-1 {ECO:0000313|Proteomes:UP000231279};
RX PubMed=29253216; DOI=10.1093/gigascience/gix125;
RA Silva-Junior O.B., Grattapaglia D., Novaes E., Collevatti R.G.;
RT "Genome assembly of the Pink Ipe (Handroanthus impetiginosus,
RT Bignoniaceae), a highly valued, ecologically keystone Neotropical timber
RT forest tree.";
RL Gigascience 7:1-16(2018).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIN22583.1}.
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DR EMBL; NKXS01000731; PIN22583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G9HYM9; -.
DR STRING; 429701.A0A2G9HYM9; -.
DR OrthoDB; 769887at2759; -.
DR Proteomes; UP000231279; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008240; F:tripeptidyl-peptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF560; SUBTILISIN-LIKE PROTEASE SBT5.6; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000231279};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..749
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013970489"
FT DOMAIN 28..108
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 140..601
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 651..746
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 206..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 149
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 222
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 543
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 749 AA; 79870 MW; 5914AABFA23AF7CE CRC64;
MNNNHFSIPS LLLLLNILLA SASAPRKVYI VYLGEHSGEK TIQDIEDDHH SYLQYVKGSK
EEAKASIIYS YKHVINGFSA LLTPQEAAAI SGMDGVISVF ESQERRVHTT RSWDFISLLE
ANFDPTQANG EALLRRANYG KDVIVGVLDT GVWPESQSFN DRGMDPVPTS WKGICQSGVA
FNTSNCNRKL IGARYYLRDY ESRNGQVQPT EDYRSPRDSS GHGTHTASTI GGRRVPNAAS
FGGFGNGTAT GGAPLVRLAI YKMCWSGVCY DGDVMSAFDD AIADGVHVIS ASIGPNTSIP
YANDIGAIGA LHAVKRNIVV SFSAGNSGPN LSTVTNTAPW VITVGASSID RVFPSQVELG
NGMIIEGQSV TPFQRRTYPL VYASQVEIPG STTSRTTGLC SYGTLSPPLV RGKAVFCLAG
DFFQALEVQR AGGAAAVLGN PRNGIGVQVT PYVIPGIVIL RNDTNRMYNY IVSNKAPTVT
LPPATTSTGA KPAPFMASFS SKGPNNVEPN ILKPDITAPG LNILAAWTEA FSPLKYFIIS
GTSMSCPHVS AIAALLKAIH PNWSSAAIRS AIMTTAKQTN NLGRPITDAL LNPATPFEYG
SGHIQPSRAA DPGLVYDASY NDYLRFLCGS IGNSLDPSFP CPRVAPPPSA LNYPSLAIAN
LRGTMTVTRN VTNVGAATSS YSVTINEPSG FSVRISPTRL NFNAVGQTLS FGITVQAQST
ARRNEFVFGS YTWSDGIHQV RSPIAVSAA
//
