ID A0A2G9N2I5_9ARCH Unreviewed; 616 AA.
AC A0A2G9N2I5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=(P)ppGpp synthetase {ECO:0008006|Google:ProtNLM};
GN ORFNames=COV47_03145 {ECO:0000313|EMBL:PIN85226.1};
OS Candidatus Diapherotrites archaeon CG11_big_fil_rev_8_21_14_0_20_37_9.
OC Archaea; Candidatus Diapherotrites.
OX NCBI_TaxID=1974407 {ECO:0000313|EMBL:PIN85226.1, ECO:0000313|Proteomes:UP000229477};
RN [1] {ECO:0000313|EMBL:PIN85226.1, ECO:0000313|Proteomes:UP000229477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG11_big_fil_rev_8_21_14_0_20_37_9
RC {ECO:0000313|EMBL:PIN85226.1};
RA Probst A.J., Ladd B., Jarett J.K., Geller-Mcgrath D.E., Sieber C.M.,
RA Emerson J.B., Anantharaman K., Thomas B.C., Malmstrom R., Stieglmeier M.,
RA Klingl A., Woyke T., Ryan C.M., Banfield J.F.;
RT "Depth-based differentiation of microbial function through sediment-hosted
RT aquifers and enrichment of novel symbionts in the deep terrestrial
RT subsurface.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIN85226.1}.
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DR EMBL; PCWY01000041; PIN85226.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G9N2I5; -.
DR Proteomes; UP000229477; Unassembled WGS sequence.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13291; ACT_4; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS51880; TGS; 1.
PE 4: Predicted;
FT DOMAIN 366..434
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT DOMAIN 544..616
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 616 AA; 70367 MW; 114474BA2B7CE13F CRC64;
MDLDQIVADF EEKCENSLGE EKTIKQALQF IRETSSKKDG ETPCRIALGL TDILLDLTQD
KETILAGLLH ESTPQFIEEK TVKEKFGNTV LEYINLINRL EKAMKFKPDD LENSQKKLII
VLSTNPNIAI LKLSKRLFLL RNLTLIQEKE KLEFIKETKK IYATLAYKLG IYSLSSEMYD
LIFKYEEPEK YDKIKKSIKI TVDSMKEAIQ KTIDTVKLTV DDAGIEAKIS GRTKTIYSTY
NKMKRKNIFV KKIYDLMAIR VIVSGIKECY EVLGIVHSLW KPTPGEFDDY IAKPKSNGYR
SLHTTVTAFD YPLEIQIRTE EMHSFAELGI ASHWRYKGTK SESKYDTKIE WVRQILDWQK
TTSEKNDMCV FSKQVFAMTP KGNVIELPEG ATVIDFAYGI HSDIGDKCKS AKINEKYVSL
DTKIENGDVV EILTSPNQTP KVGWLNYAKT QKAKQKIRSK LKIQTKKEKS NLGKRGISHA
IKTSDPRVKL GHCCSPLPGD EIVGFKTTKR KISVHRNTCK EAEKANAKKV DVVWDSKTTA
YQTELIVKSR NRVGLLQDIL SVFTKENMLV EKAYAKTSEA NTALCQFKVN VKDSQQLSKI
IEKIKKIDGV SHIYRE
//
