ID   A0A2G9NTJ8_9ARCH        Unreviewed;       331 AA.
AC   A0A2G9NTJ8;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=tRNA methyltransferase {ECO:0000313|EMBL:PIN94042.1};
GN   ORFNames=COU54_00540 {ECO:0000313|EMBL:PIN94042.1};
OS   Candidatus Pacearchaeota archaeon CG10_big_fil_rev_8_21_14_0_10_31_24.
OC   Archaea; Candidatus Pacearchaeota.
OX   NCBI_TaxID=1974438 {ECO:0000313|EMBL:PIN94042.1, ECO:0000313|Proteomes:UP000231401};
RN   [1] {ECO:0000313|Proteomes:UP000231401}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Probst A.J., Ladd B., Jarett J.K., Geller-Mcgrath D.E., Sieber C.M.K.,
RA   Emerson J.B., Anantharaman K., Thomas B.C., Malmstrom R., Stieglmeier M.,
RA   Klingl A., Woyke T., Ryan C.M., Banfield J.F.;
RT   "Depth-based differentiation of microbial function through sediment-hosted
RT   aquifers and enrichment of novel symbionts in the deep terrestrial
RT   subsurface.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIN94042.1}.
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DR   EMBL; PFCV01000011; PIN94042.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G9NTJ8; -.
DR   Proteomes; UP000231401; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR   InterPro; IPR031341; Methyltr_RsmF_N.
DR   InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR   InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR   InterPro; IPR011023; Nop2p.
DR   InterPro; IPR023267; RCMT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; TIGR00446; nop2p; 1.
DR   PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR22807:SF76; TRNA_RRNA CYTOSINE-C5-METHYLASE, NOL1_NOP2_SUN FAMILY; 1.
DR   Pfam; PF01189; Methyltr_RsmB-F; 1.
DR   Pfam; PF17125; Methyltr_RsmF_N; 1.
DR   PRINTS; PR02008; RCMTFAMILY.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:PIN94042.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PIN94042.1}.
FT   DOMAIN          38..327
FT                   /note="SAM-dependent MTase RsmB/NOP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51686"
SQ   SEQUENCE   331 AA;  37870 MW;  89173494B2CA7751 CRC64;
     MLKILFQIMS RTFKYEMKPL FEERMRKLMP LEEDFQKFSA IVHIGPRNFI RCNNLKISPK
     ELIEKLRKKW EVSQPFQGYE EIMLIESELK PGELGNSLEH VLGYYYVQEI SSMLSVLALN
     PEPEDLILDL CASPGSKTTQ IAARMQNTGT LIANDLKMDR IKILSSNLEK AGVTNAIITR
     NDAISFCLRL LKTNFKFDKI LLDAPCSGEG TLRSSPKTFN MWNHKVVNNL SRLQKKFFAN
     AIKLLKVGGT IVYSTCTHAP EENEAIVDFA LRNFPVKVET ISLPLKCRPG ITEWKNETYN
     QEVTKCCRIY PQDNDSEGFF VSKLTLLGEI K
//