ID A0A2H0ZDD5_CANAR Unreviewed; 472 AA.
AC A0A2H0ZDD5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=SAM domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B9J08_005334 {ECO:0000313|EMBL:PIS48634.1}, CA7LBN_003472
GN {ECO:0000313|EMBL:QWW24615.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS48634.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS48634.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS48634.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
RN [2] {ECO:0000313|EMBL:PIS48634.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS48634.1};
RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N.,
RA Cuomo C.A.;
RT "Candida auris genome assembly and annotation.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QWW24615.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CA7LBN {ECO:0000313|EMBL:QWW24615.1};
RA Finianos M.;
RT "Candida auris outbreak in lebanese hospital.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; PEKT02000010; PIS48634.1; -; Genomic_DNA.
DR EMBL; CP076752; QWW24615.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H0ZDD5; -.
DR STRING; 498019.A0A2H0ZDD5; -.
DR EnsemblFungi; B9J08_005334-t37_1; B9J08_005334-t37_1-p1; B9J08_005334.
DR VEuPathDB; FungiDB:B9J08_005334; -.
DR VEuPathDB; FungiDB:CJI96_0004121; -.
DR VEuPathDB; FungiDB:CJI97_005417; -.
DR VEuPathDB; FungiDB:CJJ07_003414; -.
DR VEuPathDB; FungiDB:CJJ09_004023; -.
DR VEuPathDB; FungiDB:QG37_03593; -.
DR OMA; IPIESDH; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR Proteomes; UP000825438; Chromosome IV.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01786; RA_STE50; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00314; RA; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230249}.
FT DOMAIN 7..70
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 376..449
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 71..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 51104 MW; 3BDDA212A89C1B19 CRC64;
MESFLQWDPA QVSSYIKGHI GQDVSSLFID NNIDGSLLPY ITCEHLRELG IEPLATRLKI
KKAIHSLIAG QQNSNHTSSG TPGATSTVTT PGTLSVSTNF NNHTPTVSSF GLLNNQVSLE
AITLCQILVQ DVFKKTTQAM AAAPLSTTPG SAVSTSGSLL GSASTSTDDI RKLNENFIKL
KADLNPVIRL IKDSKPLPTP TLDPGIASAP SPTSSTNSRD HEQQELSGEH PQLENLVHSL
SAHSINTNLQ DNSHQHPPSP TQSRRLSSGS VLSMGVGKIT DLSGKSSSSH RLFNKARLID
SRSAAGSPME DRLSPRDVDE IKRIEAVKPR RSSSSVLSPT SHYFHGNHSS HLKPTQGSNV
STPSASASSQ STQPLKQLKA SSDDTCLKVL QQAMKRHHIP RNHWSKYVLV ICYGDKERIL
KLTEKPVIVF KELQEHGKNP AIMLRELAPA EPDGSDKYED SRIQDEIPGG TL
//
