ID A0A2H0ZK68_CANAR Unreviewed; 1192 AA.
AC A0A2H0ZK68;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Bms1-type G domain-containing protein {ECO:0000259|PROSITE:PS51714};
GN ORFNames=B9J08_002615 {ECO:0000313|EMBL:PIS51045.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS51045.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS51045.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS51045.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIS51045.1}.
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DR EMBL; PEKT02000007; PIS51045.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H0ZK68; -.
DR STRING; 498019.A0A2H0ZK68; -.
DR EnsemblFungi; B9J08_002615-t37_1; B9J08_002615-t37_1-p1; B9J08_002615.
DR VEuPathDB; FungiDB:B9J08_002615; -.
DR VEuPathDB; FungiDB:CJI96_0000461; -.
DR VEuPathDB; FungiDB:CJI97_002669; -.
DR VEuPathDB; FungiDB:CJJ07_003968; -.
DR VEuPathDB; FungiDB:CJJ09_001477; -.
DR VEuPathDB; FungiDB:QG37_07231; -.
DR OMA; KLHVPMV; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR CDD; cd01882; BMS1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012948; AARP2CN.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR039761; Bms1/Tsr1.
DR InterPro; IPR037875; Bms1_N.
DR InterPro; IPR007034; BMS1_TSR1_C.
DR InterPro; IPR030387; G_Bms1/Tsr1_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12858; RIBOSOME BIOGENESIS PROTEIN; 1.
DR PANTHER; PTHR12858:SF2; RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08142; AARP2CN; 1.
DR Pfam; PF04950; RIBIOP_C; 1.
DR SMART; SM00785; AARP2CN; 1.
DR SMART; SM01362; DUF663; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51714; G_BMS1; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000230249};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 72..236
FT /note="Bms1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51714"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1151..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..489
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..580
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..711
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1192 AA; 136677 MW; F4C755085E83779E CRC64;
MDSSQQSNKP HRGSDGKKNT AKKKLHANGH NAKAFAVAAP KKLEKMARRT HDVNEKRYHV
PMVDRTPDDD PPPVIVAVVG PPGTGKTTLI KSLVKKLTKS TLTEVKGPIT VVSGKRRRLT
FMEVNNDMNS MIDAAKIADL VLLLVDGNFG LEMETMEFLN IAQHHGMPRV LGVATHLDLF
KSQSTLRTSK KRLKHRFWTE VYQGAKLFYL SGVLNGRYPD REILNLLRFI SVMKFRPLKW
RNEHPYLLAD RVTDLTHPQQ IAENPKTDRK VALYGYLHGT PLPSTNAHIH IAGVGDYYAH
SVEKLPDPCP TPYFEQKLDE IEREKAKAAA ESGEEVAPRR RRRKRLEDKQ KIIYAPMSDV
GGVLVDRDAV YIDVGDKQSF VAGEEKGEGE KLVTDLQEVQ KTMHERFAEG PGLQLFSNSA
HIENENELNE SSDEEEAGLL QEAGSKGRTA MRKPRLYGKS VAEDDEFDDM DDVDSDQEMD
DEEEEQPKMV EIDFGEAANG KAANDLEYAE DSELSSDDES EHYTAMARKL KGSIQRRWDI
NKLMYLDNID PAEAVRRWRQ EKVEENDEDD EEEDDIEEED EDFFKKKSTG GQSEDLDTFI
PKYPSLDELR EKFDASRIED SDDEYENGYR ILKSRLLVAP KLEEGEKAGN DENDDDDEEE
VYGDFEDLED GENHEEEKEG EEKEGDGDGD DFADFEAEEA KDEDPEAQED EENLTVEQKR
ELNAAKKAKL KMQFEDEEDR EFGADDPEGD TEADTWYEFQ KNKMAKQLEI NKAEYEDMDP
ETRTKIEGYR AGSYVKIVFE KLPCEFVENL DPEYPIVLGG LLSTESRFGI MNVRIRRHRW
HKKILKSQDP LILSLGWRRF QTIPIYTTTD SRTRNRMLKY TPEHAYCFAS FYGPLVAPNT
TFVGFNLVDQ SSTTGSFRVA ATGVVEDLNS SVEIVKKLKL VGHPYKIFRN TAFVKDMFSN
SLEVAKFEGA AIRTVSGIRG EIKRALSKPD GYFRATFEDK VLMSDTIFLK TWYPVKVKKF
YNPVTSLLLS KHNEWKGMRL TGQVRAENNI PTPIEKDSTY KKIEREERKF NPLKVPKSIR
KELPFKSQIH EAKPQKKSTY MAKRAVVVDG DEKKMRDLVN KINTLKRDKE MKRKAKKSEK
FSEKLKEIAK KEEAKKEKER ERKREYFAKQ GKKRSLESSE AGSAAFGSKR RR
//
